Objective To analyze the use of polysaccharide conjugate vaccines in China.Methods We obtained data on batches of polysaccharide conjugate vaccines released during 2007-2020 from the National Institutes for Food and Drug Control website,vaccine doses administered during 2014-2020 from the National Immunization Program Information Management System,and birth cohort population sizes during 2014-2020 from the China Statistical Yearbook.We analyzed numbers of released doses and estimated average number of doses administered per birth.Results A total of 461.204 million doses of polysaccharide conjugate vaccines were released from 2007 to 2020 in China,with an average annual increase of 5.53％.Vaccines conjugated with TT,CRM197,and OMP carrier proteins accounted for 92.63％,6.69％,and 0.68％,respectively,of the released doses.An average of 1.46 doses per birth was administered during 2014-2020,increasing from 1.17 doses per birth in 2014 to 2.51 doses per birth in 2020,and with 1.84,1.62,and 1.13 doses per birth administered in eastern,central,and western regions.Conclusions The use of polysaccharide conjugate vaccines increased from 2007 to 2020 in China,particularly in the eastern region.More attention should be paid to improving polysaccharide conjugate vaccination strategies for rational use.
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万方数据
