孕妇疫苗接种现状与展望
Status and prospects for vaccination of pregnant women
岳晨妍 1修乐欣 1李玖洪 1李克莉 1Lance Rodewald 1郑徽 1王富珍 1尹遵栋1
作者信息
- 1. 传染病溯源预警与智能决策全国重点实验室,中国疾病预防控制中心,北京 102206;中国疾病预防控制中心免疫规划中心,北京 100050
- 折叠
摘要
孕妇发生新型冠状病毒感染、流感等疾病后发展为重症或死亡的风险更高,并且可导致不良妊娠结局.大多数疫苗的起始接种月龄为婴儿出生后6周龄以上,婴儿可能存在免疫空白期,疾病的感染风险增高.孕妇接种部分疫苗可以有效预防疫苗可预防疾病的发生,保护孕妇、胎儿和婴儿.本文总结了国际上广泛推荐孕妇使用的疫苗的安全性和有效性、疫苗针对疾病的负担以及部分国家包括中国的孕妇疫苗接种现状,讨论了孕妇参与疫苗临床研究和疫苗接种的挑战,对中国实施孕妇疫苗接种的前景进行了展望.
Abstract
Illnesses during pregnancy,such as COVID-19 or influenza,can lead to severe disease,complications,and adverse pregnancy outcomes in pregnant women.Most infant vaccinations start no earlier than 6 weeks after birth,and therefore infants may have an immunity gap period with an increased risk of disease prior to vaccination.Maternal vaccinations may effectively protect pregnant women,fetuses,and infants from vaccine-preventable diseases.In this article,we summarize the safety and effectiveness of vaccines widely recommended for pregnant women,burdens of vac cine-targeted diseases,and the status of maternal vaccination in some countries including China.We discuss challenges in vaccine clinical trials and vaccination of pregnant women and provide prospects for maternal vaccination in China.
关键词
孕妇/疫苗/疫苗接种Key words
Pregnant women/Vaccine/Vaccination引用本文复制引用
基金项目
中国CDC公共卫生应急反应机制的运行(102393220020010000017)
出版年
2024
NETL
NSTL
万方数据