首页|超声引导下高强度聚焦超声消融治疗子宫肌瘤疗效及术后生活质量

超声引导下高强度聚焦超声消融治疗子宫肌瘤疗效及术后生活质量

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目的:探究超声引导下高强度聚焦超声(HIFU)与腹腔镜子宫肌瘤剔除术(LM)治疗子宫肌瘤的临床疗效,并分析患者术后生活质量.方法:收集2021年1月-2022年1月本院收治有生育要求的子宫肌瘤患者100例,根据手术方式不同分为腹腔镜下子宫肌瘤剔除术的LM组以及使用采用超声引导下进行高强度聚焦超声消融的HIFU组,比较两组治疗疗效、围术期指标、术后不良反应、术后6个月生活质量以及肌瘤残留及复发情况.结果:HIFU组治疗总有效率(100.0%)高于LM组(92.0%),手术时间(55.8±12.8min)、住院时间(1.7±0.8d)及术后至完全恢复时间(4.9±2.2d)少于 LM 组(80.4±12.3min、2.8±0.9d、7.3±0.6d),术中出血量(0)低于 LM 组(127.6±22.2ml),下腹疼痛发生率(24.0%)低于LM组(44.0%)(均P<0.05).HIFU组与LM组术后3个月肌瘤残留率(2.0%、4.0%)和术后6个月肌瘤复发率(0、2.0%)无差异(P>0.05).术后6个月,HIFU组UFS-QOL问卷评分和SF-36量表评分均优于LM组,月经量评分(92.81±26.79分)少于LM组(114.65±28.61分),月经量过多发生率(6.0%)低于LM组(22.0%)(均P<0.05).结论:经阴道HIFU子宫肌瘤剔除术疗效和安全性更好,术后患者生活质量更高,值得推广用于有生育需求患者.
Efficacy of high-intensity focused ultrasound ablation by ultrasound-guided for treating patients with uterine myomas and the postoperative quality of life of the patients
Objective:To explore the clinical efficacy of high-intensity focused ultrasound(HIFU)ablation by ultra-sound-guided and laparoscopic myomectomy(LM)for treating patients with uterine myomas of,and to analyze the postoperative quality of life of the patients.Methods:100 patients with uterine myoma who had fertility needs from January 2021-January 2022 were collected.According to the different methods of surgery,the patients were given treatment of laparoscopic myomectomy in group A and the patients were given treatment of HIFU ablation by ultra-sound guided in group B.The curative effect,the perioperative index,the postoperative adverse reactions,the quality of life in 6 months after surgery and the situations of fibroids residue and recurrence of the patients were compared be-tween the two groups.Results:The total effective rate(100.0%)of the patients in group B was significantly higher than that(92.0%)of the patients in group A.The operation time(55.8±12.8min),the hospital stay(1.7±0.8d)and the time to complete recovery(4.9±2.2d)of the patients in the group B were significantly shorter than those(80.4± 12.3min,2.8±0.9d and 7.3±0.6d)of the patients in group A,and the intraoperative blood loss(0)of the patients in the group B was significantly less than that(127.6±22.2ml)of the patients in group A.The incidence of lower abdomi-nal pain(24.0%)of the patients in the group B was significantly lower than that(44.0%)of the patients in group A(all P<0.05).There were no significant differences in the residual rate of myoma in 3 months after surgery(2.0%vs.4.0%)and the recurrence rate in 6 months after surgery(0 vs.2.0%)of the patients between the two groups(P>0.05).In the 6th month after surgery,the UFS-QOL score and SF-36 scale score of the patients in the group B were significantly better than those of the patients in group A.The menstrual volume score(92.81±26.79 points)and the in-cidence of menorrhagia(6.0%)of the patients in the group B were significantly lower than those(114.65±28.61 points and 22.0%)of the patients in group A(all P<0.05).Conclusion:The HIFU ablation by transvaginal ultrasound-guided for treating the patients with uterine myomas had better efficacy and safety compared to those of the conven-tional laparoscopic myomectomy,and the postoperative quality of life of the patients is higher,which is worth popular-izing for the patients with uterine myomas who have fertility needs.

Laparoscopy uterine myomectomyUltrasound-guided high-intensity focused ultrasoundClinical efficacyQuality of lifeRecurrence after surgeryResidual myoma

忻超、邵碧红、施吉耀

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宁波市海曙区人民医院(315010)

腹腔镜子宫肌瘤剔除术 超声引导下高强度聚焦超声 临床疗效 生活质量 术后复发 肌瘤残留

2024

中国计划生育学杂志
国家人口计生委科学技术研究所

中国计划生育学杂志

CSTPCD
影响因子:1.759
ISSN:1004-8189
年,卷(期):2024.32(1)
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