首页|间苯三酚联合缩宫素在单胎足月初产妇阴道试产中应用效果

间苯三酚联合缩宫素在单胎足月初产妇阴道试产中应用效果

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目的:探究间苯三酚联合缩宫素在单胎足月初产妇阴道试产中的应用效果.方法:采用随机数字表法将2021年1月-2023年1月在本院接受阴道试产且阴道试产期间出现第一产程异常的197例初产妇分为单一组(98例)和联合组(99例),分别予缩宫素及间苯三酚联合缩宫素治疗,比较两组用药后产程进展情况、宫颈水肿发生率、用药后宫缩强度及母婴结局.结果:联合组用药至进入活跃期时间(77.3±35.5 min)、活跃期时间(100.3±51.3 min)、用药至宫口开全时间(55.4±25.7 min)均短于单一组(117.6±51.5 min、155.3±71.3 min、85.4±43.2 min),宫颈水肿比例(2.0%)低于单一组(9.2%),宫缩强度为强比例(76.8%)高于单一组(63.3%),自然分娩率(95.0%)高于单一组(84.7%),产时(150.4±55.4ml)及产后 6 h(250.5±38.3ml)出血量均低于单一组(200.5±44.3ml、291.4±40.6ml)(均P<0.05);两组产钳助产比例、胎位异常、巨大儿、头盆不称比例无差异(P>0.05),胎儿宫内窘迫比例联合组(0)低于单一组(7.1%)(P<0.05);两组新生儿出生后1 min、5 min Apgar评分及新生儿体重均无差异(P>0.05).结论:苯三酚联合缩宫素用于阴道试产第一产程异常初产妇,可有效促进产程进展,提升自然分娩率,降低产时及产后出血量.
Application effect of the phloroglucinol combined with oxytocin used in vaginal trial delivery of primiparous women with single fetus of full-term pregnancy
Objective:To study the application effect of the phloroglucinol combined with oxytocin used in vaginal trial delivery of primiparous women with single fetue of full-term pregnancy.Methods:197 primiparous women with single fetus of full-term pregnancy who wanted vaginal trial delivery were selected and were divided into two groups by ran-dom number table method when these women experienced abnormalities in the first stage of labor during the trial deliv-ery period from January 2021 to January 2023.98 women in the control group were treated with oxytocin,and 99 women in the study group were treated with phloroglucinol combined with oxytocin.The progress of labor,the inci-dence of cervical edema,the intensity of uterine contractions after medication of the women and the maternal and infant outcomes were compared between two groups.Results:The time from the medication used to entering the active phase of labor(77.3±35.5 min),the duration of the active phase of labor(100.3±51.3 min),and the time from the medica-tion used to the full cervical opening(55.4±25.7 min)of the women in the study group were significantly shorter than those(117.6±51.5 min,155.3±71.3 and 85.4±43.2 min)of the women in the control group.The proportion of the cervical edema(2.0%)of the women in the study group was significantly lower than that(9.2%)of the women in the control group,and the proportion of the strong uterine contraction(76.8%)of the women in the study group was sig-nificantly higher than that(63.3%)of the women in the control group.The natural delivery rate(95.0%)of the women in the study group was significantly higher than that(84.7%)of the women in the control group,and the vol-ume of the blood loss during labor(150.4±55.4ml)and in 6 hours after delivery(250.5±38.3ml)of the women in the study group were significantly lower than those(200.5±44.3ml and 291.4±40.6ml)of the women in the control group(all P<0.05).There were no significant differences in the proportions of forceps delivery,abnormal fetal position,macrosomia and cephalopalvic disproportion of the women between the two groups(P>0.05).The proportion of the fetal distress(0)of the women in the study group was significantly lower than that(7.1%)of the women in the con-trol group(P<0.05).There were no significant differences in the neonatal Apgar scores at 1 min and 5 min after birth and the neonatal weight between the two groups(P>0.05).Conclusion:The application of phloroglucinol combined with oxytocin used in vaginal trial delivery of primiparous women with single fetus of full-term pregnancy can effective-ly promote their labor progress,improve their natural delivery rate,and reduce their cesarean section rate and amount of postpartum hemorrhage.

PrimiparaVaginal trial deliveryPhloroglucinolOxytocinStage of laborAmount of bleedingDelivery outcomes

石晓、林芳、张芳、杨慧丽

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青岛市胶州中心医院(266300)

初产妇 阴道试产 第一产程异常 间苯三酚 缩宫素 产程 出血量 分娩结局

2022-2024年青岛市市级临床重点专科妇产专科

2024

中国计划生育学杂志
国家人口计生委科学技术研究所

中国计划生育学杂志

CSTPCD
影响因子:1.759
ISSN:1004-8189
年,卷(期):2024.32(2)
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