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多普勒超声脑胎盘率、脐动脉血流诊断胎儿生长受限价值

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目的:分析多普勒超声脑胎盘率(CPR)、脐动脉血流诊断胎儿生长受限(FGR)价值.方法:选取2022年7月-2023年7月于本院产前检查诊断为FGR的90例孕妇为观察组,正常妊娠孕妇80例为对照组,均行多普勒超声检测脐动脉搏动指数(PI)、阻力指数(RI)、收缩期最大血流速度/舒张末期血流速度(S/D)及CPR并比较,统计妊娠不良结局,采用受试者工作曲线(ROC)评估PI、RI、S/D及CPR对FGR的诊断价值.结果:两组PI、RI、S/D及CPR值随孕周增加而下降,且观察组孕32~33+6周、34~36+6周、37~40周的PI、RI、S/D值均高于对照组,CPR低于对照组(P<0.05).ROC曲线分析显示,37~40周超声PI、RI、S/D、CPR联合诊断FGR的曲线下面积为0.957,敏感度97.5%,均高于单独指标检测(P<0.05).观察组新生儿窒息、低体重率及Apgar评分低于对照组(P<0.05).结论:CPR联合脐动脉血流可提高FGR的诊断效能和敏感度.
Diagnostic value of the cerebroplacental ratio and the umbilical artery blood flow parameters detected by Doppler ultra-sound of pregnant women for their fetal growth restriction
Objective:To analyze the diagnostic value of the cerebroplacental ratio(CPR)and the umbilical artery blood flow detected by Doppler ultrasound of pregnant women for their fetal growth restriction(FGR).Methods:90 preg-nant women with FGR diagnosed by antenatal examination in hospital were selected in observation group,and 80 nor-mal pregnant women were selected in control group between July 2022 and July 2023.The values of umbilical artery pulsatilityindex(PI),resistance index(RI),maximum systolic blood flow velocity to end-diastolic blood flow velocity(S/D)ratio and CPR of the women in the two groups were detected by Doppler ultrasound.The adverse pregnancy outcomes of the women in the two groups were counted.The values of PI,RI,S/D and CPR,and the incidence of ad-verse pregnancy outcomes of the women were compared between the two groups.Receiver operator characteristic(ROC)curve was used to evaluate the predictive value of the values of PI,RI,S/D and CPR of the women for their FGR.Results:The PI,RI,S/D and CPR values of the women in the two groups had decreased with the increase of their gestational weeks.The values of PI,RI and S/D of the women in the observation group during 32-33+6 gestation-al weeks,34-36+6 gestational weeks and 37-40 gestational weeks were significantly higher than those of the women in the control group,and the CPR value of the women in the observation group was significantly lower(P<0.05).ROC curve analysis showed that the area under the curve of the combination of the values of PI,RI,S/D and CPR of the women for diagnosing their FGR during 37-40 gestational weeks was 0.957,and the sensitivity of which was 97.5%,and both of which were significantly higher than those of the PI value,the RI value,the S/D value or the CPR value a-lone(P<0.05).The rates of the neonatal asphyxia and low birth weight,and the neonatal Apgar score in the observa-tion group were significantly lower than those in the control group(P<0.05).Conclusion:The CPR combined with umbilical artery blood flow parameters values of the pregnant women for diagnosing their FGR can increase the diagnostic efficacy and the diagnostic sensitivity.

Fetal growth restrictionDoppler ultrasoundCerebroplacental ratioUmbilical artery blood flowDiag-nostic valuePrognosis

张兰、李晓庆

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四川省资阳市第一人民医院(641300)

胎儿生长受限 多普勒超声 脑胎盘率 脐动脉血流 诊断价值 预后

2024

中国计划生育学杂志
国家人口计生委科学技术研究所

中国计划生育学杂志

CSTPCD
影响因子:1.759
ISSN:1004-8189
年,卷(期):2024.32(3)
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