Effects of the dialectical Bushenzengye decoction combined with L-carnitine for treating patients with asthenospermia on their semen parameters and the related indexes of their in vitro fertilization and embryo transplantation
Objective:To explore the effects of the dialectical Bushenzengye decoction combined with L-carnitine for treating patients with asthenospermia on their semen parameters and the related indexes of their in vitro fertilization.Methods:94 patients with asthenospermia who wanted the treatment of IVF cycle were selected and were divided into control group(41 cases with the treatment of L-carnitine for 12 weeks)and the study group(53 cases with the treat-ment of the dialectical Bushenzengye decoction combined with L-carnitine for 12 weeks)according to the different treatment methods from January 2020 to January 2022.The treatment effect,the semen quality analysis before and af-ter treatment,the sexual function and IVF cycle related indexes of the patients were compared between the two groups.Results:The semen volume(3.71±0.75ml),the sperm concentration(30.05±5.75 106 cells/ml),the sperm survival rate(58.63±10.14%),the rate of the a+b level sperm(66.65±10.45%)of the patients in the study group after treatment were significantly higher than those(3.08±0.89ml,27.63±5.07 106 cells/ml,53.17±8.45%and 60.74± 8.71%)of the patients in the control group.The scores of the erection confidence(3.65±0.46 points),the erection time(3.89±0.35 points),the erection maintenance time(3.63±0.45 points),the difficulty of sexual intercourse(4.35 ±0.25 points),the sexual satisfaction(4.05±0.21 points)and the total score(19.57±1.72 points)of the patients in the study group were significantly higher than those(3.37±0.31points,3.41±0.29 points,3.23±0.23 points,4.11± 0.16 points,3.33±0.15 points and 17.45±1.14 points)of the patients in the control group.The fertilization rate(82.8 ±5.1%),the high-quality embryo rate(56.9±10.3%),the number of transferrable embryos(2.4±0.5 pieces)and the clinical pregnancy rate(60.0%)of the patients in the study group were significantly higher than those(81.0± 3.7%,48.5±8.0%,1.5±0.5 pieces and 37.5%)of the patients in the control group.The total effective rate(90.6%)of the patients in the study group was significantly higher than that(73.2%)of the patients in the control group(all P<0.05).Conclusion:The dialectical Bushenzengye decoction combined with L-carnitine for treating the patients with asthenospermia can improve their semen quality and sexual function,and which is conducive to improving the indica-tors related to IVF cycle and increasing the success rate of IVF.
AsthenospermiaL-carnitineBushenzengye decoctionSemen qualitySexual functionIn vitro fertiliza-tion and embryo transplantation