首页|分娩前血清钙、磷和D-二聚体水平预测宫缩乏力性产后出血价值

分娩前血清钙、磷和D-二聚体水平预测宫缩乏力性产后出血价值

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目的:探究产妇分娩前血清钙、磷、D-二聚体水平在预测宫缩乏力性产后出血中的临床价值.方法:回顾性收集2018年10月-2023年10月本院收治的分娩产妇106例,按照是否发生宫缩乏力性产后出血分为观察组(n=21,发生宫缩乏力性产后出血)与对照组(n=85,无宫缩乏力性产后出血),收集产妇病历资料,比较两组产前血清钙、磷、D-二聚体水平,采用多因素logistic回归分析法筛选造成产妇宫缩乏力性产后出血的危险因素,分析产前血清钙、磷、D-二聚体水平预测宫缩乏力性产后出血价值.结果:观察组分娩前血清钙(2.39±0.31 mmol/L)、磷(1.27±0.30 mmol/L)水平均低于对照组(2.66±0.28 mmol/L、1.53±0.35 mmol/L),D-二聚体(0.40±0.09 mg/L)高于对照组(0.32±0.10 mg/L)(均P<0.05);logistic回归分析显示,低血清钙、低磷水平、高D-二聚体、高龄、高体质指数、产程延长是造成产妇发生宫缩乏力性产后出血的危险因素(P<0.05).血清钙、磷、D-二聚体联合预测宫缩乏力性产后出血的曲线下面积0.912,敏感度95.2%、特异性50.6%,其预测效能高于单独指标(均P<0.05).结论:产妇分娩时低钙和磷、高D-二聚体、年龄较大、产程较长、高BMI是造成宫缩乏力性产后出血的危险因素,而血清钙、磷、D-二聚体水平联合检测可有效预测宫缩乏力性产后出血的发生.
Values of the levels of serum calcium,phosphorus and D-dimer of pregnant women before delivery for predicting their u-terine inertia-induced postpartum hemorrhage
Objective:To explore the values of the levels of serum calcium,phosphorus and D-dimer of pregnant women before delivery for predicting their uterine inertia-induced postpartum hemorrhage.Methods:106 women who had delivered in hospital from October 2018 to October 2023 were collected in this study retrospectively.These women were divided in 21 cases with uterine inertia-induced postpartum hemorrhage in observation group and 85 cases without uterine inertia-induced postpartum hemorrhage in control group according to whether the uterine inertia-induced post-partum hemorrhage occurred or not.The medical records of the women in the two groups were collected.The levels of the prenatal serum calcium,phosphorus and D-dimer of the women were compared between the two groups.Multivari-ate Logistic regression analysis was used to screen the risk factors of the uterine inertia-induced postpartum hemor-rhage of the women.The values of the levels of the prenatal serum calcium,phosphorus and D-dimer of the women for predicting their uterine inertia-induced postpartum hemorrhage was analyzed.Results:The levels of the prenatal serum calcium(2.39±0.31 mmol/L)and phosphorus(1.27±0.30 mmol/L)of the women in the observation group were sig-nificantly lower than those(2.66±0.28 mmol/L and 1.53±0.35 mmol/L)of the women in the control group.The pre-natal serum D-dimer level(0.40±0.09 mg/L)of the women in the observation group was significantly higher than that(0.32±0.10 mg/L)of the women in the control group(all P<0.05).Logistic regression analysis showed that the low serum calcium and phosphorus levels,the high D-dimer level,the advanced age,the high body mass index value and the prolonged labor duration of the women were the risk factors of their uterine inertia-induced postpartum hemorrhage(P<0.05).The area under the curve(AUC),the sensitivity and the specificity of the combined levels of the serum calcium,phosphorus,and D-dimer of the women for predicting their uterine inertia-induced postpartum hemorrhage were 0.912,95.2%and 50.6%,respectively,and the predictive efficacy of which was significantly higher than that of the serum calcium level,the phosphorus level or the D-dimer level alone(all P<0.05).Conclusion:The low levels of calcium and phosphorus,and the high D-dimer levels before delivery,the advanced age,the prolonged labor duration and the high body mass index value of the women are the risk factors of their uterine inertia-induced postpartum hem-orrhage.The combined detection of the serum calcium,phosphorus,and D-dimer levels of the women can effectively predicting the occurrence of their uterine inertia-induced postpartum hemorrhage.

Uterine inertia-induced postpartum hemorrhageCalciumPhosphorusD-dimerPredictive value

况炯、杨学铭、黄萍、张潇云、马世平

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四川省德阳市妇幼保健院(618000)

宫缩乏力性产后出血 D-二聚体 预测价值

2024

中国计划生育学杂志
国家人口计生委科学技术研究所

中国计划生育学杂志

CSTPCD
影响因子:1.759
ISSN:1004-8189
年,卷(期):2024.32(4)
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