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女性癌症患者生育力保存技术

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随着近年癌症患者生存率的不断提高以及相关辅助生殖技术的发展,针对女性癌症患者的生育力保存也成为了现阶段的研究热点.本文对近10年的文献研究中报道的女性生育力保存技术进行综述.包括卵巢组织冷冻与移植、卵巢组织体外激活技术、卵巢抑制、卵巢移位术、人工卵巢、未成熟卵母细胞冷冻和胚胎冷冻技术等生育力保存技术的有效性和安全性,并讨论比较了每种方法的优、缺点.以期将来能为女性癌症患者选择合适的生育力保存技术提供支持.
Fertility preservation techniques of female cancer patients
With the increasing survival rate of the cancer patients and the development of assisted reproduction tech-niques,the fertility preservation of the female cancer patients has become a hot research topic at this stage.The pur-pose of this paper is to review the female fertility preservation techniques reported in the literatures in the last decade.A comprehensive literatures search was conducted,covering the effectiveness and safety of the female fertility preser-vation techniques,such as the ovarian tissue cryopreservation and transplantation,the ovarian tissue in vitro activa-tion,the ovarian suppression,the ovarian transposition,the artificial ovaries,the immature oocyte cryopreservation and the embryo cryopreservation.This article also discusses and compares the advantages and disadvantages of each method of the fertility preservation techniques to provide the supports for selecting the appropriate fertility preservation techniques for the female cancer patients in the future.

Fertility preservationOvarian tissue cryopreservation and transplantationOvarian tissue in vitro activa-tionOvarian suppressionImmature oocyte cryopreservationMature oocyte cryopreservationEmbryo cryopreserva-tionOvarian transpositionArtificial ova

王申、陈静、李友筑

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重庆医科大学国际医学院(401334)

厦门大学附属第一医院生殖医学中心

生育力保存 卵巢组织冷冻移植 卵巢组织体外激活技术 卵巢抑制 未成熟卵母细胞冷冻 成熟卵母细胞冷冻 胚胎冷冻技术 卵巢移位术 人工卵巢

2024

10.3969/j.issn.1004-8189.2024.04.048

中国计划生育学杂志
国家人口计生委科学技术研究所

中国计划生育学杂志

CSTPCD
影响因子：1.759
ISSN：1004-8189
年,卷(期)：2024.32(4)
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