A descriptive analysis of prepregnancy medication among Chinese women with pregnancy intention during 2013-2019
Objective:To analyze medication among Chinese women with pregnancy intention,and to provide the data support for promoting the preconception health of the women.Methods:A total of 871 152 women who had participa-ted in the National Free Pre-pregnancy Checkups Project(NFPCP)and had self-reported medication during 2013-2019 were included as the study objects.All the self-reported medications were parsed with the reference of National Essen-tial Drugs List published in 2018.Descriptive epidemiological method was used to analyze the characteristics of the prepregnancy medication of the women,and Chi-square test was used to analyze the distribution differences of the med-ication according to the baseline characteristics.Results:Up to 2.2％of the women with planning pregnancy had repor-ted medication usage,with a diverse range of drug types being reported.The prepregnancy medications primarily com-prised of vitamin/mineral drugs(64.1％),followed by obstetrics,gynecology,and family planning drugs(7.5％),an-timicrobials(6.8％),hormones and drugs influencing the endocrine system(6.7％),analgesic/antipyretic/anti-in-flammatory/anti-rheumatic/anti-gout drugs(5.4％)and traditional Chinese herbal medicine(5.0％).The women with advanced age,Han nationality,high school education level above,urban household registration,non-farmer occu-pation,delivery history,history of adverse pregnancy,or overweight or obese had tend to have the higher usage rates of antimicrobial drugs,hormones,drugs influencing the endocrine system,analgesic and antipyretic/anti-inflammatory/anti-rheumatic/anti-gout drugs,and traditional Chinese herbal medicine.Conclusion:The diversity of prepregnancy medications is complex,and which is presenting challenges for ensuring the safe medication usage and the health coun-selling.During the pre-pregnancy health counselling,attention should be directed towards the medication usage among the women with advanced age,Han nationality,high school education level above,urban household registration,non-farmer occupation,delivery history,history of adverse pregnancy,and overweight or obese.It is crucial for identifying the potential risks of medication-induced pregnancy and embryonic toxicity,thus decreasing the occurrence of the ad-verse pregnancy outcomes associated with the prepregnancy medication used of the women.
Planning pregnancyMedication safetyDescriptive epidemiologyPre-pregnancy health
NETL
NSTL
万方数据
