维生素D缺乏孕妇规范补充维生素D预防妊娠期代谢性疾病效果及其妊娠结局分析
Effect of vitamin D standard supplementation for preventing the metabolic diseases during pregnancy of pregnant women with vitamin D deficient and the pregnancy outcomes analysis
俎晓霞 1陈肖静 1申慧军 1张鸣华1
作者信息
摘要
目的:规范补充维生素D预防妊娠期代谢性疾病效果.方法:回顾性分析本院2022年1-9月收治的422例产妇临床资料,均于孕16周化验血清25-羟基维生素D水平提示维生素D不足,根据产后调查问卷将产妇是否规范补充维生素D分为规范组及不规范组各211例,常规产科干预、营养指导,定期产前检查至分娩,孕晚期32周复查血清25-羟基维生素D水平.观察两组产妇孕期代谢性疾病发生、孕晚期维生素D缺乏情况、产妇分娩方式及分娩不良结局、新生儿不良结局、新生儿Apgar评分、产妇满意率.结果:规范组孕期代谢性疾病发生率低于不规范组,孕晚期维生素D缺乏发生率(1.0％)低于不规范组(4.3％),剖宫产率(10.0％)低于不规范组(19.5％),产妇(2.4％)及新生儿(1.4％)不良结局低于不规范组(7.6％、6.6％),产妇满意率(97.6％)高于不规范组(92.9％)(均P＜0.05).结论:孕期规范补充维生素D可降低妊娠期代谢性疾病发生,进而改善妊娠结局与新生儿结局,产妇较为认可.
Abstract
Objective:To study the effect of vitamin D standard supplementation for preventing the metabolic diseases during pregnancy of pregnant women with vitamin D deficient.Methods:The clinical data of 422 puerperas admitted to hospital from January to September 2022 were analyzed retrospectively.The serum 25 hydroxyvitamin D level of the puerperas during 16 getational weeks was tested for diagniosing their vitamin D deficiency.According to the postpar-tum questionnaire on the puerperas whether regularly supplemented vitamin D or not during pregnancy,these puer-peras were divided into the control group and the observation group(211 cases in each group).These puerperas in the two groups were given routine obstetric intervention,nutritional guidance,the regular antenatal examination until to delivery and the detection of the serum 25 hydroxyvitamin D of the puerperas during 32 gestational weeks.The inci-dence of the metabolic diseases during pregnancy,the vitamin D deficiency during the third trimester of pregnancy,the maternal delivery mode,the adverse delivery outcomes,the neonatal adverse outcomes,the neonatal Apgar score,and the satisfaction of the puerperas in the two groups were observed.Results:The incidence of metabolic diseases of the puerperas in the observation group during pregnancy was significantly lower than that of the puerperas in the control group.The incidence of vitamin D deficiency during the third trimester of pregnancy(1.0％),the rate of uterine deliv-ery(10.0％),the adverse maternal outcomes(2.4％)and the adverse newborns outcomes(1.4％)of the puerperas were significantly lower than those(4.3％,19.5％,7.6％and 6.6％)of the puerperas in the control group.The satis-faction rate(97.6％)of the puerperas in the observation group was significantly higher than that(92.9％)of the puer-peras in the control group(all P＜0.05).Conclusion:The vitamin D standard supplementation during pregnancy of the pregnant women with vitamin D deficient can decrease their metabolic diseases occurrence,thereby which can improve the maternal and neonatal outcomes,and is more recognized by the women.
关键词
维生素D/规范补充/妊娠期代谢性疾病/妊娠结局/满意率Key words
Vitamin D/Standard supplementation/Metabolic diseases during pregnancy/Satisfaction引用本文复制引用
出版年
2024
NETL
NSTL
万方数据