首页|剖宫产术后地塞米松、右美托咪定复合罗哌卡因行腹横肌平面阻滞镇痛效果

剖宫产术后地塞米松、右美托咪定复合罗哌卡因行腹横肌平面阻滞镇痛效果

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目的:探究地塞米松、右美托咪定复合罗哌卡因行腹横肌平面阻滞(TAPB)在剖宫产术后镇痛效果.方法:选择2021年4月-2023年4月本院行剖宫产手术产妇80例,手术结束后均行超声引导下双侧TAPB,按照随机数字表法分成右美托咪定组(40例)和地塞米松组(40例),分别给予右美托咪定复合罗哌卡因或地塞米松复合罗哌卡因行TAPB.比较两组下床活动时间、住院时间、首次镇痛泵按压时间、24h内镇痛泵有效按压次数和舒芬太尼累积用量、产妇满意度,静息/运动术后疼痛程度(VAS)、术后恢复质量量表(QoR40)评分和不良反应发生.结果:地塞米松组下床活动时间(7.71±0.86h)、住院时间(5.39±0.41d)、24h镇痛泵有效按压次数(2.01±1.31次)、24h舒芬太尼累积用量(46.39±0.72μg)均低于右美托咪定组(8.93±1.15h、6.05±0.72d、2.73±1.62 次、48.33±0.63μg),首次镇痛泵按压时间(689.72±68.17min)和产妇满意度(8.11±0.87分)均高于右美托咪定组(552.63±52.15min、6.33±1.23分),术后6h、12h、24h、48h静息状态下和运功状态下的VAS评分均低于右美托咪定组,舒适度、情绪、自理能力、社会交往、疼痛各项评分和QoR-40总分(169.52±7.01分)均高于右美托咪定组(152.17±7.23分)(均P<0.05);不良反应发生率两组无差异(P>0.05).结论:剖宫产术后地塞米松复合罗哌卡因行TAPB镇痛效果更佳,能有效延长镇痛时间,缓解术后疼痛,提高术后恢复质量,应用较安全.
Analgesia effect of transversus abdominis plane block with the combined dexamethasone,dexmedetomidine and ropivacaine for puerperae after cesarean section
Objective:To explore the analgesia effect of transversus abdominis plane block(TAPB)with the combined dexamethasone,dexmedetomidine and ropivacaine for puerperae after cesarean section.Methods:A total of 80 puerpe-rae who had undergone cesarean section in the hospital were enrolled as the research objects between April 2021 and A-pril 2023.After the surgery,all the puerperae were given ultrasound-guided bilateral TAPB for analgesia.According to the random number table method,these puerperae were divided into group D(40 cases with dexmedetomidine com-bined with ropivacaine for TAPB)and group S(40 cases with dexamethasone combined with ropivacaine for TAPB).The time of getting out of bed,the hospitalization stay,the time of the first analgesic pump compression,the number of the analgesic pump effective compression within postoperative 24h,the cumulative dosage of sufentanil,the mater-nal satisfaction,the scores of visual analogue scale(VAS)under rest/exercise state and the quality of recovery 40 questionnaire(QoR40)score,and the incidence of adverse reactions of the puerperae were compared between the two groups.Results:The time of getting out of bed(7.71±0.86 h),the duration of hospital stay(5.39±0.41d),the num-ber of effective pressing analgesia pump within postoperative 24h(2.01±1.31 times)and the cumulative dosage of sufentanil used within postoperative(46.39±0.72μg)of the puerperae in group S were significantly lower than those(8.93±1.15h,6.05±0.72d,2.73±1.62 times and 48.33±0.63μg)of the puerperae in group D.The first analgesic pump pressing time(689.72±68.17min)and the maternal satisfaction(8.11±0.87)of the puerperae in group S were significantly higher than those(552.63±52.15min and 6.33±1.23)of the puerperae in group D.At 6h,12h,24h and 48h after operation,the VAS scores under rest/exercise state of the puerperae in group S at postoperative 6h,12h,24h and 48h were significantly lower than those of the puerperae in group D.The scores of comfort,emotion,self-care ability,social interaction,pain and QoR-40 of the puerperae in group S were significantly higher than those of the pu-erperae in group D.The total QoR-40 score(169.52±7.01 points)of the puerperae in group S was significantly higher than that(152.17±7.23)of the puerperae in group D(all P<0.05).There was no significant difference in the inci-dence of the adverse reactions of the puerperae between the two groups(P>0.05).Conclusion:Dexamethasone com-bined with ropivacaine for TAPB of the puerperae after cesarean section has better analgesia effect,which can effective-ly prolong the analgesia time,relieve the postoperative pain and improve the postoperative recovery quality of the puer-perae,and with the better safety.

Caesarean sectionPostoperative analgesiaRopivacaineTransversus abdominis plane blockDexametha-soneDexmedetomidineRopivacaine

汪伟、程勤耘、杜伏杨、程典萍

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安徽省合肥市第八人民医院(238000)

剖宫产术 术后镇痛:腹横肌平面阻滞 地塞米松 右美托咪定 罗哌卡因

安徽省重点研究和开发计划项目

1804h08020267

2024

中国计划生育学杂志
国家人口计生委科学技术研究所

中国计划生育学杂志

CSTPCD
影响因子:1.759
ISSN:1004-8189
年,卷(期):2024.32(7)
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