Effect and safety of labor analgesia at different timing of primiparas with hypertensive disorder complicating pregnancy
Objective:To analyze the application effect and safety of labor analgesia at different timing of primiparas with hypertensive disorder complicating pregnancy(HDP).Methods:From January 2023 and December 2023,213 primiparas with HDP who gave birth in hospital were selected and were randomly divided into two groups.The labor analgesia begun of 71 primiparas in group A at their cervix＜3cm and the labor analgesia begun of 142 primiparas in group B at their cervix ≥3cm.The delivery mode,the duration of labor,the maternal and neonatal situations and the anesthesia related adverse reactions of the primiparas were compared between the two groups.At the entry of the oper-ation room(T0),at 30 minutes after analgesia(T1),at 2h after analgesia(T2)and at full opening of the cervix(T3),the pain degree of the primiparas in the two groups were evaluated by visual analogue scale(VAS)score and the values of heart rate(HR)and mean arterial pressure(MAP)of the primiparas in the two groups were also monitored.Results:There were no significant differences in the durations of the first,the second,the third and the total stages of labor of the primiparas between the two groups(P＞0.05).The VAS scores of the primiparas in group A at T1-T3(5.31±1.02 points,2.81±0.33 points and 2.89±0.35 points)were significantly lower than those(6.39±1.21 points,4.34±0.81 points and 4.41±0.82 points)of the primiparas in group B.The values of HR and MAP(91.95±6.64 beats/min and 94.24±7.32 mmHg)of the primiparas in group A at T3 were significantly lower than those(94.24±7.32 beats/min and 94.55±7.78 mmHg)of the primiparas in group B(all P＜0.05).There were no significant differ-ences in the postpartum hemorrhage volum and the adverse reactions rate of the primiparas,and the neonatal birth weight and Apgar score between the two groups(P＞0.05).Conclusion:Compared with those at the active phase of the labor,the labor analgesia of the primiparas with HDP begins at the latentperiod of the labor is safe and feasible,and which can better relieve the labor pain and control the blood pressure and heart rate of the primiparas,and without affecting the labor process and the maternal and infant's safety.
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