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针刺联合补肾健脾法治疗多囊卵巢综合征效果观察

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目的:探究针刺腹部穴位联合补肾健脾法对多囊卵巢综合征(PCOS)患者月经周期、血清鸢尾素水平及卵巢功能的影响.方法:选取90例多囊卵巢综合征(PCOS)患者为研究对象,随机分为西药组(30例)、中药组(30例)及联合组(30例),其中西药组给予炔雌醇环丙孕酮片治疗,中药组给予补肾健脾法治疗,联合组在中药组的基础上给予腹针治疗.比较治疗后3组月经周期、血清鸢尾素水平及卵巢功能.结果:联合组的总有效率(96.67%)显著高于西药组(73.33%)、中药组(76.67%)(P<0.05);与治疗前比较,治疗后3组促黄体生成素(LH)、睾酮(T)水平显著降低,月经周期显著缩短,且联合组显著低于西药组、中药组(P<0.05);治疗后3组卵泡刺激素(FSH)、雌二醇(E2)水平均显著升高,且联合组显著高于西药组、中药组(P<0.05);与治疗前比较,三组血清鸢尾素水平显著降低,且联合组显著低于西药组、中药组(P<0.05);与治疗前比较,治疗后3组卵巢体积、卵泡个数均显著降低,且联合组显著低于西药组、中药组(P<0.05);与治疗前比较,治疗后3组内膜厚度、搏动指数(PI)均显著增大,且联合组显著大于西药组、中药组(P<0.05);治疗后3组阻力指数(RI)显著降低,且联合组显著低于西药组、中药组(P<0.05);治疗后,随访3组患者6个月,联合组月经正常率、妊娠率均显著高于西药组、中药组(P<0.05).结论:腹针联合补肾健脾法可有效调节患者性激素水平,促使月经周期恢复正常,促进卵泡发育成熟、正常排卵及妊娠,改善子宫内膜容受性,降低血清鸢尾素水平,效果显著.
Effect of the acupuncture combined with kidney tonifying and spleen strengthening method for treating patients with poly-cystic ovarian syndrome
Objective:To exploring the effects of the acupuncture at abdominal acupoints combined with kidney tonify-ing and spleen strengthening(KTSS)method for treating patients with polycystic ovarian syndrome(PCOS)on their menstrual cycle,serum Iridin level and ovarian function.Methods:90 patients with PCOS who were admitted to the hospital were selected and were randomly divided into three groups(30 cases in each group)from March 2020 to April 2022.The patients in group A were given the treatment of ethinylestradiol cycloproterone tablets,the patients in group B were given the treatment of KTSS method,and the patients in group C were given the treatment of KTSS method combined with the acupuncture at abdominal acupoints.The menstrual cycle situation,the serum Iridin level and the o-varian function of the patients after treatment were compared among the three groups.Results:The total effective rate(96.7%)of the patients in group C was significantly higher than that(73.3%)of the patients in group A,or that(76.7%)of the patients in group B(P<0.05).The levels of luteinizing hormone(LH)and testosterone(T)of the patients in the three groups after treatment had decreased significantly,and the menstrual cycle of the patients in the three groups after treatment had shortened significantly,and which of the patients in group C were significantly lower than those of the patients in group A and in group B(P<0.05).The levels of follicle stimulating hormone(FSH)and estradiol(E2)of the patients in the three groups after treatment had increased significantly,and which of the patients in group C were significantly higher than those of the patients in group A and in group B(P<0.05).The serum irisin level of the patients in the three groups after treatment had decreased significantly,and which of the patients in group C was significantly lower than that of the patients in group A and in group B(P<0.05).The ovarian volume and the number of follicles of the patients in the three groups after treatment had decreased significantly,and which of the pa-tients in group C were significantly lower than those of the patients in group A and in group B(P<0.05).The endom-etrial thickness and the pulsatility index(PI)value of the uterine artery of the patients in the three groups after treat-ment had increased significantly,and which of the patients in group C were significantly higher than those of the pa-tients in group A and in group B(P<0.05).The resistance index(RI)value of the uterine artery of the patients in the three groups after treatment had decreased significantly,and which of the patients in group C was significantly lower than that of the patients in group A and in group B(P<0.05).After treatment,the patients in the three groups were followed up for 6 months,the rates of normal menstruation and pregnancy of the patients in group C were significantly higher than those of the patients in group A and in group B(P<0.05).Conclusion:The acupuncture at abdominal acu-points combined with KTSS method for treating patients with PCOS can effectively regulate their sex hormones levels,promote their menstrual cycle recovery,follicular maturation,normal ovulation and pregnancy,improve their endome-trial receptivity and reduce their serum irisin level,and with remarkable effectiveness.

Polycystic ovary syndromeTonifying the kidney and strengthening the spleenAcupuncture at abdominal acupointMenstruationSerum irisinOvarian function

何丹、刘咏梅、李媛媛

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四川省达州市中心医院(635000)

多囊卵巢综合征 补肾健脾法 腹针 月经 血清鸢尾素 卵巢功能

达州市中心医院2022年度院级科研项目

2022YJ05

2024

中国计划生育学杂志
国家人口计生委科学技术研究所

中国计划生育学杂志

CSTPCD
影响因子:1.759
ISSN:1004-8189
年,卷(期):2024.32(7)