Effect of Ziyinbuyang sequential method combined with western medicine for treating patients with polycystic ovary syn-drome and its influence on the ovarian reserve function of the patients
Objective:To explore the effect of Ziyinbuyang sequential method combined with western medicine for trea-ting patients with polycystic ovary syndrome(PCOS),and to study its influence on the ovarian reserve function of the patients.Methods:126 patients with PCOS were selected and were divided into control group(63 cases)and study group(63 cases)by simple randomization(lottery method)from August 2021 to October 2022.The patients in the con-trol group were treated with western medicine therapy,while the patients in the study group were given Ziyinbuyang sequential method combined with western medicine therapy.The clinical efficacy,the traditional Chinese medicine(TCM)symptoms scores,the indicators of ovarian reserve,ovarian and follicular change,and the adverse reactions rate of the patients were compared between the two groups.The patients in the two groups were followed up for 1 year,and the ovulation and the pregnancy status of the patients in the two groups were recorded.Results:The total ef-fective rate(93.7％)of the patients in the study group after treatment was significantly higher than that(81.0％)of the patients in the control group.The TCM symptom scores of the patients in the two groups after treatment had decreased significantly,and which of the patients in the study group were significantly lower than those of the patients in the con-trol group.The levels of follicle-stimulating hormone,inhibin B and anti-Mullerian hormone,and the value of luteini-zing hormone/follicle-stimulating hormone of the patients in the two groups after treatment had decreased significant-ly,and which of the patients in the study group were significantly lower than those of the patients in the control group.The values of ovarian volume and AFC of the patients in both groups after treatment had decreased significantly,and which(5.18±0.84mm and 8.63±1.27)of the patients in the study group were significantly lower than those(5.83±0.57mm and 10.45±1.82)of the patients in the control group(all P＜0.05).There was no significant difference in the incidence of adverse reactions(4.8％vs.1.6％)of the patients between the two group(P=0.310).Within 1 year of follow-up,the ovulation rate(88.9％)and the pregnancy rate(39.7％)of the patients in the study group were signifi-cantly higher than those(71.4％and 22.2％)of the patients in the control group(all P＜0.05).Conclusion:Ziyin-buyang sequential method combined with western medicine for treating patients with PCOS improve their clinical symptoms,promote their ovarian reserve function,and enhance their ovulation and pregnancy rate,and with good safety.
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