Research progress of nitric oxide for treating neonate with persistent pulmonary hypertension
Neonatal persistent pulmonary hypertension(PPHN)is a common critical disease during the neonatal peri-od,with the mortality rate of 20.6％.At present,the main drug treatment for the neonatal PPHN is the application of the pulmonary vasodilator.Nitric oxide,as a selective pulmonary vasodilator,has been used as the preferred drug for the treatment of the neonatal PPHN,but nitric oxide also has certain limitations.This paper mainly reviews the advan-tages and disadvantages of NO for treating the neonatal PPHN,as well as the clinical effect and the existing problems of NO combined with other drugs for treating the neonatal PPHN.
万方数据
维普
