Efficacy of Xiao'er Tuihuang Jianpi free-fried granule combined with bifidobacterium triple viable powder for auxiliary treating neonatal jaundice
Objective:To analyze the auxiliary application effect of Xiao'er Tuihuang Jianpi free-fried granule combined with bifidobacterium triple viable powder for treating neonatal jaundice.Methods:96 neonates with jaundice who has born in the hospital were selected and were divided into two groups(48 cases in each group)according to simple ran-dom sampling method from December 2022 to December 2023.The neonates in the control group were given bifidobac-terium triple viable powder and the neonates in the study group were given Xiao'er Tuihuang Jianpi free-fried granule combined with bifidobacterium triple viable powder.The efficacy,the levels of the T lymphocyte subsets indexes be-fore and after treatment and the rate of adverse reactions of the neonates were compared between groups.Results:The total effective rate(95.8％)of the neonates in the study group after treatment was significantly higher than that(81.3％)of the neonates in the control group.The time of hospital stay(5.65±0.70 d)of the neonates in the study group after treatment was significantly less than that(7.01±0.86 d)of the neonates in the control group.The de-creased degree of the bilirubin level(8.96±1.12 mg/dl)of the neonates in the study group after treatment was signifi-cantly higher than that(7.04±0.97mg/dl)of the neonates in the control group.The levels of CD3+,CD4+,CD4+/CD8+of the neonates in the study group after treatment were significantly higher than those of the neonates in the con-trol group(all P＜0.05).There was no significant difference in the CD8+level of the neonates before and after treat-ment between the two groups.There was no significant difference in the total incidence of the adverse reactions(6.2％vs.18.8％)of the neonates between the two groups(P＞0.05).Conclusion:The application of Xiao'er Tuihuang Jianpi free-fried granule combined with bifidobacterium triple viable powder for auxiliary treating the neonatal jaundice has better effect,and which has good regulatory effect on the levels of the T lymphocyte subsets of these neonates,and without increasing the adverse reactions incidence.
万方数据
维普
