Effects of the goal-directed health promotion combined with the personalized medical nutrition therapy for pregnant women with gestational diabetes mellitus on their postnatal glucose-lipid metabolism prognosis
Objective:To observe the effects of the goal-directed health promotion combined with the personalized med-ical nutrition therapy for pregnant women with gestational diabetes mellitus(GDM)on the postnatal glucose-lipid me-tabolism prognosis.Methods:60 pregnant women with GDM were given the goal-oriented health education combined with the personalized medical nutrition therapy intervention were selected in the study group,and another 60 pregnant women with GDM were given the conventional health education combined with the personalized medical nutrition thera-py intervention were selected in the control group from February 2021 to May 2023.The scores of the behavioral change of the women in the two groups before and after intervention were assessed.The total incidence of the adverse pregnancy outcomes of the women in the two groups was counted.The levels of the glucose and lipid metabolism and the pancreatic islet function of the women in the two groups before intervention and in the postpartum 12th weeks were detected.Results:After intervention,the scores of the self-weight management,the diet control and the moderate ex-ercise of the women in the two groups had increased significantly,and which of the women in the study group were significantly higher than those of the women in the control group.The total incidence of the adverse pregnancy out-comes(3.3％)of the women in the study group was significantly lower than that(13.3％)of the women in the control group(all P＜0.05).In the postpartum 12th week,the levels of the fasting blood glucose and the 1h and 2h postpran-dial blood glucose,and the glycosylated hemoglobin value of the women in the two groups had decreased significantly,and which(5.01±0.44 mmol/L,7.20±0.51 mmol/L,6.67±0.43 mmol/L and 5.64％±0.59％)of the women in the study group were significantly lower than those(5.54±0.63 mmol/L,7.94±0.69 mmol/L,7.38±0.51 mmol/L and 6.27％±0.74％)of the women in the control group.The high-density lipoprotein cholesterol and the pancreatic islet β-cell function index of the women in the two groups had increased significantly,and which(1.64±0.28 mmol/L and 64.01±7.73)of the women in the study group were significantly lower than those(1.39±0.26 mmol/L and 56.85±6.84)of the women in the control group.The levels of triglyceride(TG)and total cholesterol(TC),the value of ho-meostasis model assessment of insulin resistance(HOMA-IR),and the low-density lipoprotein cholesterol(LDL-C)of the women in the two groups had decreased significantly,and which(1.15±0.22 mmol/L,4.35±0.58 mmol/L,2.18±0.32 and 2.98±0.72 mmol/L)of the women in the study group were significantly lower than those(1.49±0.31 mmol/L,4.63±0.67 mmol/L,2.64±0.37 and 3.34±0.81 mmol/L)of the women in the control group(all P＜0.05).Conclusion:The goal-directed health promotion combined with the personalized medical nutrition therapy for the preg-nant women with GDM can promote their behavioral changes,can reduce their incidence of the adverse pregnancy out-comes,and can improve their postpartum glucolipid metabolism and pancreatic islet function.
Gestational diabetes mellitusGoal-directed health pubicity and educationPersonalized medical nutrition therapyGlucolipid metabolismAdverse pregnancy outcomes
万方数据
维普
