Analysis on characteristics of diarrhea caused by Diarrheagenic Escherichia coli infection in Beijing Sentinel Hospital,2021
Objective To analyze the epidemiological and clinical characteristics of diarrhea cases infected by Di-arrheagenic Escherichia coli(DEC)in Beijing Sentinel Hospital in 2021,and to provide a basis for effective disease pre-vention and control.Methods Fecal or anal swab samples of diarrhea cases were collected from 36 active monitoring hospi-tals for foodborne diseases in Beijing in 2021.The information included gender,age,address,onset time,personal basic information,dietary history,and clinical characteristics were also collected.DEC in the collected fecal or anal swab samples were isolated,cultured,and identified.Adopt x2 or Fisher's exact probability test were used to compare the positive detec-tion rates of different subtypes of DEC.Results In 2021,5697 stool or anal swab samples of diarrhea cases were collected from Foodborne illness surveillance in Beijing.The positive detection rate of DEC was 7.65％(436/5697),with the high-est positive detection rate in the group aged 20-39(x2=18.804,P＜0.001).From the perspective of age distribution,ETEC positive cases in group aged 20-39 were higher than those in other age groups(x2=36.769,P＜0.001).Based on regional distribution,most cases of EAEC and EPEC infections came from the suburbs(x2=50.679,x2=19.659,P＜0.001),cases of ETEC infection were mainly distributed in urban areas(x2=13.420,P=0.001).From a seasonal distri-bution perspective,EAEC,ETEC,and EPEC infections occurred more frequently in summer than in other seasons(x2=32.096,x2=89.339,x2=16.876,P＜0.001),EHEC infection mainly occurred in spring(x2=10.976,P＜0.001).In terms of suspected dietary history characteristics,cases of ETEC infection often consumed packaged drinking wa-ter,alcohol,beverages,and frozen foods(x2=41.837,P＜0.001),EAEC infected people had taken more Baby food(x2=24.229,P=0.007).In terms of clinical characteristics,cases with abdominal pain had a higher detection rate of ETEC(x2=8.017,P=0.005),the detection rate of EAEC was higher in cases with nausea or vomiting(x2=5.701,P=0.017;x2=4.160,P=0.041).Conclusion The cases of diarrhea caused by DEC infection in Beijing Sentinel Hospi-tal have seasonal and population epidemiological characteristics,which can be combined with suspected food exposure infor-mation and clinical characteristics of different subtypes of DEC infection cases to provide a basis for food safety and health ed-ucation and clinical diagnosis.
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