The effect of sedentary behavior on cognitive frailty in older adults:a meta-analysis
Objective To explore the effect of sedentary behavior on cognitive frailty in the elderly with meta-analysis,and to provide reference for the formulation of intervention strategies for the prevention of cognitive frailty.Methods Pubmed,Web of science,Embase,CNKI,Wanfang and VIP databases were searched from the establishment of the database to October 2022,and RevMan 5.3 software was used for statistical analysis after screening literature,extracting data and eval-uating the quality of the included studies.Results Five studies with a sample size of 4225 were included,of which 2 were cross-sectional studies and 2 were cohort studies.The results of meta-analysis showed that sedentary behavior was associated with cognitive frailty in the elderly(OR=3.38,95％CI:1.36-8.41).The results of subgroup analysis showed that in different countries[China(OR=2.26,95％CI:1.62-3.17),Peru(OR=509.43,95％CI:31.65-8200.42)],hospital(OR=509.43,95％CI:31.65-8200.42),community(OR=2.22,95％CI:1.61-3.07)),and sedentary measures[Physical Activity Scale for the Elderly(OR=509.43,95％CI:31.65-8200.42),sedentary behavior time(OR=2.26,95％CI:1.62-3.17)],follow-up time[Follow-up Time＜1 Year(OR=2.22,95％CI:1.61-3.07),follow-up time ≥1 Year(OR=509.43,95％CI:31.65-8200.42)],study type[Cross-sectional Study(OR=2.26,95％CI:1.62-3.17)],all of which showed that sedentary behavior was positively correlated with cognitive frailty in the elderly(P＜0.05).Conclusion Sedentary behavior is related to the occurrence of cognitive frailty in the elderly,and it is suggested that follow-up studies should pay attention to the internal mechanism of sedentary behavior and cognitive frailty,so as to provide further evidence support for the prevention of cognitive frailty.
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