目的 了解重庆市吸毒人群丙型病毒性肝炎(丙肝)防治知识知晓率及丙肝病毒(hepatitis C virus,HCV)感染情况,并分析HCV感染的影响因素,为下一步防治工作提供科学参考.方法 基于2021年重庆市艾滋病哨点监测工作,采用连续抽样法,2021年4-6月对重庆市18岁及以上的吸毒人群开展问卷调查,调查内容主要包括基本人口学信息、丙肝防治知识及行为学特征,并采血检测HCV抗体.采用SPSS 20.0软件分析人群丙肝知识知晓情况以及HCV感染率的影响因素.结果 共调查1823人,其丙肝防治知识知晓率为49.9％,HCV抗体阳性率为43.1％.多因素Logistic分析结果显示,女性感染率高于男性(OR=1.8,95％CI:1.1～3.0,P＜0.05);30～39岁(OR=10.3,95％CI:3.9～27.6)、40～49 岁(OR=40.4,95％CI:15.2～107.5)、≥50 岁(OR=41.3,95％CI:15.3～111.7)年龄组感染率均高于≤29岁年龄组人群(P均＜0.05);未婚(OR=2.5,95％CI:1.7～3.7)、离异或丧偶(OR=1.5,95％CI:1.1～2.2)人群的感染率高于在婚(P均＜0.05);知晓丙肝防治知识者感染率高于不知晓者(OR=1.5,95％CI:1.1～2.0,P＜0.05).非共用针具注射吸毒者(OR=23.5,95％CI:16.9～32.7)及共用针具注射吸毒者(OR=23.1,95％CI:13.7～38.9)感染率高于非注射吸毒者(P均＜0.05).与近1年未发生过吸毒后性行为者相比,近1年发生吸毒后性行为(OR=2.0,95％CI:1.4～2.9,P＜0.05)感染HCV的风险更高.结论 重庆市吸毒人群丙肝防治知识知晓率较低,HCV感染率较高,注射吸毒及吸毒后性行为是感染HCV的危险因素,建议今后要加强吸毒人群丙肝知识宣教及危险行为干预工作.
Awareness of knowledge related hepatitis C prevention and control and infection among drug users in Chongqing City
Objective To investigate the awareness of knowledge related hepatitis C prevention and control and in-fection of HCV among drug users,and to provide scientific basis for the prevention in Chongqing City.Methods Based on the AIDS sentinel surveillance work in Chongqing in 2021,a questionnaire survey was conducted among drug users aged 18 and above in Chongqing from April to June by using continuous sampling method.The survey contents included socio-demo-graphic characteristics,knowledge of hepatitis C prevention and control,behavioral characteristics,and blood collection for HCV antibody detection.SPSS 20.0 was used for statistical analysis.Results A total of 1823 objects were investigated,and the awareness rate about hepatitis C prevention and control was 49.9％.The positive rate of HCV was 43.1％,the rate in women was higher than that in men(OR=1.8,95％Cl:1.1-3.0,P＜0.05).People aged 30-39(OR=10.3,95％CI:3.9-27.6),40-49(OR=40.4,95％CI:15.2-107.5)and over 50 years old(OR=41.3,95％CI:15.3-111.7)had higher positive rate of HCV than 29 years and under(P＜0.05),The unmarried(OR=2.5,95％CI:1.7-3.7)and divorced or widowed(OR=1.5,95％CI:1.1-2.2)had higher rate than the married(P＜0.05).Injecting drug users who did not share needles(OR=23.5,95％CI:16.9-32.7)and who shared needles(OR=23.1,95％CI:13.7-38.9)had higher positive HCV rate than non-injecting drug users(P＜0.05).The risk was higher among those who had sex after drug use in the last 1 year(OR=2.0,95％CI:1.4-2.9,P＜0.05)compared with those who had not.Conclusion The awareness rate about hepatitis C prevention and control among drug users was low,and the infection in drug users was high.Injecting drugs and having sex after drug use were risk factors for drug users.It is sugges-ted that knowledge publicity of hepatitis C prevention and control and behavior intervention should be strengthened in future.
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