首页|Retrospective:Advances and Opportunities of 3D Bioprinting in China over Three Decades
Retrospective:Advances and Opportunities of 3D Bioprinting in China over Three Decades
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Three-dimensional(3D)bioprinting,which has been applied in tissue engineering and regenerative medicine,uses biomaterials,cells,and other essential components to manufacture organs and tissues with specific biolog-ical functions and complex structures.Over the past 30 years,researchers have developed new 3D bioprinting technologies with improved manufacturing capabilities and expanded applications.Chinese research teams con-tributed significantly to this process.In this paper,we first reviewed the development history and major mile-stones in 3D bioprinting,categorizing them into two main strategies:"biomaterial-based indirect assembly"and"living cell-based direct assembly".This review further delved into the technical principles,recent advancements,advantages,disadvantages,and applications of each type of bioprinting technology.Finally,the challenges and future directions of 3D bioprinting were summarized to guide future research in China and foster advancements in this dynamic field.
3D bioprintingBiofabricationBioinkRegenerative medicineDisease modeling
Xianhao Zhou、Yongcong Fang、Ting Zhang、Zhuo Xiong
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Biomanufacturing Center,Department of Mechanical Engineering,Tsinghua University,Beijing,100084,China
Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing,Beijing,100084,China
"Biomanufacturing and Engineering Living Systems"Innovation International Talents Base(111 Base),Beijing,100084,China
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