In recent years,serving as the front-line defense against imported cases,China Customs adheres to the requirement of"the Customs must stand firm in preventing and controlling epidemics at ports",and strictly implement the task of"multi-disease prevention".There is an urgent need for a unified laboratory monitoring and early warning platform that can not only conduct in-depth pathogen identification and precise tracing,but also undertake routine monitoring of infectious diseases at ports in the future.The rise and application of Next Generation Sequencing(NGS)technology in the field of early warning provides a new perspective for infectious disease surveillance at customs ports.This article introduces the architecture,advantages and disadvantages of traditional and new infectious disease monitoring and early warning platforms around the world,and puts forward some design thoughts for the establishment of a new platform within the customs system based on NGS,aiming to provide reference for accurate prevention and control of epidemics at ports and realize precise quarantine.
whole genome sequencingmetagenomic Next-Generation Sequencing(mNGS)monitoring and early warning of infectious diseasescustoms
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