重复经颅磁刺激对酒依赖者的影响

Effects of repeated transcranial magnetic stimulation on alcohol-dependent patients

谷贤龙 ¹王蕾²

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作者信息

1. 温州市第七人民医院精神科,浙江温州 325000
2. 温州市第七人民医院心理科,浙江温州 325000
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摘要

目的:研究重复经颅磁刺激(rTMS)对酒依赖者心理渴求、自我效能感(SE)及复饮的影响.方法:选择2021年4月～2022年6月于我院接受治疗的酒依赖患者86例,依据随机数字表法将86例酒依赖患者分为rTMS组(n=43)、对照组(n=43).对照组行常规支持及替代治疗,rTMS组在对照组基础上行rTMS治疗.观察2组治疗前、治疗5周后及治疗后6个月酒精依赖、心理渴求、自我效能感及复饮情况;观察2组治疗后6个月,复饮以及再住院情况.结果:治疗完成后,2组酒精依赖戒断评估表(CIWA-Ar)、酒精依赖筛查量表(MAST)、心理渴求以匹兹堡睡眠质量指数量表(PSQI)、宾夕法尼亚酒精渴求量表(PACS)评分均较治疗前降低(P＜0.05),且rTMS组CIWA-Ar、MAST、PSQI、PACS 评分均低于对照组(P＜0.05);治疗后 6 个月,rTMS 组 CIWA-Ar、MAST、PSQI、PACS评分均低于对照组(P＜0.05),rTMS组CIWA-Ar、MAST、PSQI、PACS评分与治疗完成后差异无统计学意义,对照组CIWA-Ar、MAST、PSQI、PACS评分均高于治疗完成后(P＜0.05).治疗完成后,2组一般自我效能感量表(GSES)评分均较治疗前升高,且rTMS组GSES评分均高于对照组(P＜0.05);治疗后6个月,rTMS组GSES评分高于对照组(P＜0.05),rTMS组GSES评分与治疗完成后差异无统计学意义,对照组GSES评分低于治疗完成后(P＜0.05).治疗期间,2组均无显著副反应发生.治疗后6个月,rTMS组复饮以及再住院率均低于对照组(P＜0.05).结论:rTMS治疗可有助于降低酒依赖患者酒精依赖程度及对酒精的心理渴求,缓解患者生理心理上的痛苦,增强其SE,降低复饮及再住院率.

Abstract

Objective:To study the effects of repeated transcranial magnetic stimulation(rTMS)on psychological crav-ing,self-efficacy and relapse of alcohol dependence.Methods:A total of 86 alcohol-dependent patients treated in our hospi-tal from April 2021 to June 2022 were selected and divided into rTMS group(n=43)and control group(n=43)by the random number table method.The control group received routine support and alternative therapy,and the rTMS group re-ceived rTMS therapy on the basis of the control group.Alcohol dependence,psychological craving,self-efficacy and relapse were observed before treatment,after treatment and 6 months after treatment.Relapse and re-hospitalization after 6 months of treatment were observed in both groups.Results:After treatment,CIWA-Ar,MAST,PSQI and PACS scores in both groups were lower than those before treatment,and CIWA-Ar,MAST,PSQI and PACS scores in the rTMS group were lower than those in the control group.After 6 months of treatment,CIWA-Ar,MAST,PSQI and PACS scores in the rT-MS group were lower than those in the control group(P＜0.05).CIWA-Ar,MAST,PSQI and PACS scores in the rTMS group were not different from those after treatmen,while CIWA-Ar,MAST,PSQI and PACS scores in the control group were higher than those after treatment.After treatment,GSES scores in both groups were higher than those before treat-ment,and GSES scores in the rTMS group were higher than those in the control group.After 6 months of treatment,GSES score in the rTMS group was higher than that in the control group(P＜0.05).There was no significant difference in the GSES scores in the rTMS between 6 months of treatment and after treatment completion,while the GSES scores in the control group were lower than those after treatment.During treatment,no significant side effects occurred in both groups.After 6 months of treatment,the rates of re-drinking and re-hospitalization in rTMS group were lower than those in the control group(P＜0.05).Conclusion:rTMS can help reduce the degree of alcohol dependence and psychological thirst for alcohol,relieve the physiological and psychological pain of patients,enhance their SE,and reduce the rate of relapse and re-hospitalization.

关键词

重复经颅磁刺激/酒依赖/心理渴求/自我效能感/复饮

Key words

repetitive transcranial magnetic stimula-tion/alcohol dependence/psychological desire/self-ef-ficacy/re-drinking

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基金项目

温州市科研项目(Y20210755)

出版年

2024

中国康复

中国残疾人康复协会华中科技大学同济医学院

中国康复

CSTPCD

影响因子：1.154

ISSN：1001-2001

参考文献量10

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