首页|Multifunctional polyeugenol-based nanoparticles with antioxidant and antibacterial properties

Multifunctional polyeugenol-based nanoparticles with antioxidant and antibacterial properties

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Over the past few decades,extensive scientific has been dedicated to polymer synthesis employing renewable resources.In this study,we devised and synthesized multifunctional polyeugenol-based nanoparticles,exhibiting remarkable antioxidant and antibacterial properties.The grafting of eugenol onto the nanoparticle surface was achieved via a thiol-ene chemical reaction with a grafting rate of 3.5％.To comprehend the properties of the synthesized nanoparticles,we employed Fourier transform infrared spectroscopy,X-ray photoelectron spectroscopy and pyrolysis-gas chromatography mass spectrometry.Subsequent scanning electron microscopic and transmission electron microscopic analyses revealed the presence of a crosslinked structure within the polyeugenol-based nanoparticles,as well as a heteroge-neous microsphere structure on the surface.Due to the inherent crosslinking structure,the polyeugenol-based nanoparticles demonstrated robust the resistance to solvents,as ascertained through thermog-ravimetric analysis and solvent resistance tests.Notably,nitrogen adsorption/desorption studies confirmed the adsorption capacity of the polyeugenol-based nanoparticles,rendering them potentially suitable for drug transport applications.Moreover,the assays for assessing cytocompatibility and reactive oxygen species scavenging activities demonstrated better performance of the eugenol-based nano-particles compared to eugenol.Furthermore,the polyeugenol-based nanoparticles exhibited certain bactericidal activities against Escherichia coli,Staphylococcus aureus,and Fusobacterium nucleatum.Consequently,these observations indicated the nontoxic nature and expansive application prospects of the polyeugenol-based nanoparticles in the domains of medicine and food preservation.This work presented a pioneering concept for the development of antioxidant and antibacterial multifunctional polymer materials derived from eugenol.

Polyeugenol-based nanoparticlesBactericidal activitiesCytocompatibility

Qiaoqiao Lan、Xuying Zhang、Jiaming Liang、Wei Wang、Leili Lv、Jiamin He、Zefeng Wang、Chunsheng Qu

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The People's Hospital of Lishui,Lishui,323000,China

College of Ecology,Lishui University,Lishui,323000,China

R&D Center of Green Manufacturing New Materials and Technology of Synthetic Leather Sichuan University-Lishui University,Lishui,323000,China

Lishui Science and Technology Bureau projectLishui Lvgu Famous Doctor Talent Training projectScience and Technology Research Projects of Lishui Science and Technology BureauZhejiang Province"13th Five Year Plan"Provincial Industry University Cooperation Collaborative Education project

2019SJZC372020GYX02

2024

10.1016/j.partic.2023.08.012

颗粒学报(英文版)
中国颗粒学会　中国科学院过程工程研究所

颗粒学报(英文版)

CSTPCD
影响因子：0.632
ISSN：1674-2001
年,卷(期)：2024.87(4)
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