首页|Biosynthesized Persicaria odorata-silver nanoparticles supported zeolite Y as biocompatible antibacterial agent against Cutibacterium acnes

Biosynthesized Persicaria odorata-silver nanoparticles supported zeolite Y as biocompatible antibacterial agent against Cutibacterium acnes

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Conventionally synthesized silver nanoparticles(AgNP)imposed an alarming effect on the environment and caused toxicity to humans.However,the use of zeolite(zeoY)as a support system could increase its biocompatibility and reduce its toxicity.Hence,green synthesis of AgNP using Persicaria odorata leaves extract supported on zeolite Y has been prepared by an in situ synthesis technique.The phytochemical compounds in the optimized leaf extract concentration of 1％ and volume of 0.9 mL reduced the silver ions to AgNP within the zeolite Y pores.Morphological observation revealed the incorporation of AgNP in the zeolite Y(average size:18.51 nm).The release of AgNP exhibited antibacterial activity on C.acnes at a concentration lower than 1 g L-1 which is also dependent on the electrolyte.AgNP-zeoY promoted cell proliferation in vitro and it has a non-irritating effect when tested in the in vivo skin irritation model.

Silver nanoparticlesBiosynthesisZeoliteAntibacterialBiocompatible

Muhammad Hariz Asraf、Nik Ahmad Nizam Nik Malek、Muhammad Redza Mohd Radzi、Hendra Susanto

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Department of Biosciences,Faculty of Science,Universiti Teknologi Malaysia,81310 Skudai,Johor,Malaysia

Department of Biosciences,Faculty of Science,Universiti Teknologi Malaysia,81310,Skudai,Johor,Malaysia

Centre for Sustainable Nanomaterials(CSNano),Ibnu Sina Institute for Scientific and Industrial Research(ISI-SIR),Universiti Teknologi Malaysia,81310,UTM,Johor,Malaysia

Department of Biology,Faculty of Mathematics and Natural Sciences,Universitas Negeri Malang,Indonesia

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Malaysia Ministry of Higher Education and Universiti Teknologi Malaysia under Industry/International Incentive Grant(ⅢG)Professional Development Research University

Vot No 02M61Vot No 06E23

2024

10.1016/j.partic.2024.05.015

颗粒学报(英文版)
中国颗粒学会　中国科学院过程工程研究所

颗粒学报(英文版)

CSTPCD
影响因子：0.632
ISSN：1674-2001
年,卷(期)：2024.93(10)