Progress in the evolution and vaccine research of Marek's disease
Marek's disease(MD)is an infectious and lymphoid hyperplasia disease of chicken caused by Marek's disease virus(MDV),and characterized by T-lymphoid tumors,immunosuppression,and paralysis.MD is a widespread disease of chickens in poultry farming countries and regions around the world,causing huge economic losses to the poultry industry.Control of the disease mainly relies on vaccine immunization,and it is a challenge because of the continuous evolution of MDV towards stronger virulence,which leads to the need for vaccines to be constantly updated.This article introduces the research progress of evolution and vaccines of MD.