猪蓝耳病,即猪繁殖与呼吸综合征(porcine reproductive and respiratory syndrome,PRRS),是一种严重危害养猪业的重要传染病.该病于1987年首先出现在美国中西部,随后在中欧地区开始流行,目前已经遍布全球养猪发达地区,该病历经30多年的流行,仍未得到有效控制.国内外许多学者对猪繁殖与呼吸综合征病毒(PRRS virus,PRRSV)开展了相关研究,研究内容涉及PRRSV起源与演化、基因组结构与功能、致病与免疫机制、疫苗创制和疫病防控等各方面.本文综述了近年来国内外PRRS的科研方向和进展,旨在为进一步研究提供依据.
Porcine reproductive and respiratory syndrome:past and present
Porcine reproductive and respiratory syndrome(PRRS),also named swine blue-ear disease,has caused huge economic losses and continues to threaten the swine industry worldwide.The disease was first reported in the United States in 1987,then the epidemic began in European countries,and it has now spread throughout most of the pig-raising countries.In the past 30 years,many researchers have carried out studies on PRRSV,including its origin and evolution,genome structure and function,pathogenesis and immune mechanism,vaccine development,and disease prevention and control.In this article,the research progress on PRRSV was reviewed,aiming to provide a basis for further research.
porcine reproductive and respiratory syndromeviral originepidemiologyvaccine developmentdisease control
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