Mitochondrial dyshomeostasis in cardiac aging and related diseases
Cardiac aging is characterized by cardiac functional decline and pathophysiological myocardial remodeling over time,which is one of the major risk factors for cardiac diseases.An increasing number of studies have elucidated the critical role of mitochondrial dysfunction in the pathobiologies of aging-related cardiac diseases.This review mainly focuses on mitochondrial dyshomeostasis in cardiac aging and summarizes the remarkable progress in understanding the impacts of mitochondrial dyshomeostasis on aging-related cardiac diseases and the potential perspectives of mitochondrial-targeted interventions and therapeutic strategies for aging-related cardiac disease.
万方数据
维普
