The human brain is one of the most complex systems in nature.Exploring the structure and function of the brain is an ultimate frontier for humans to understand themselves,and it is of great significance to the development of scientific and technological innovation,as well as the progress of human civilization.Manned spaceflight is an important field of modern scientific and technological revolution,and space giants including the United States and Russia have used space resources to carry out brain research.The construction of China Space Station will provide a systematic platform for space brain research.This review summarizes the progress previously made on brain development,cognitive functions,effects of biological rhythm and sleep on brain function,and multi-brain interaction mechanisms,in real or simulated space environment.We also provide a brief summary and perspective on the space brain science project in China.
space environmentbrain scienceweightlessnessbrain developmentcognitiongroup brain synergy