Progress in biological sample resources development of birth cohort in China
The natural population growth rate in China has continued to decline in recent years,and this trend may continue in the foreseeable future.The incidence of infertility remains high,and the impact of assisted reproductive therapy on the health of the offspring is not fully evaluated.Therefore,reproductive health,maternal and child health related research needs to be strengthened urgently.Birth cohort,a classical study design for association study between maternal exposure and health of offspring,has been used to explore the impact of genetic,environmental,psychosocial,nutritional and other factors on pregnancy outcomes and offspring outcomes in early life.As a complex research platform,several countries have made remarkable achievements in birth cohort.In China,several birth cohorts have started.We have gained some successful experience and accumulated a large number of biological samples,which is critical important for reproductive health,maternal and child health related research.In this review,we comprehensively introduced the progress as well as challenges of birth cohort and biological sample resources in China and globally.We also we look forward to the future of biological sample resources in the birth cohort,with a view to providing important reference for the high-quality development of Chinese population.
birth cohortbiological samplehuman genetic resourcessharing and cooperation
NETL
NSTL
万方数据
