Advances in organoid and related biospecimen repository research
Biobank plays an important role in basic life science and clinical research as a repository for collecting,storing,and managing all kinds of samples from living organisms.As an emerging model for individualized research in recent years,the inclusion of organoids in biobank is of great importance to further enhance the reliability,diversity and expandability of biobank.The use of individualized organoids as biobank resources can better simulate the complex physiological and pathological functions of different human organs.As an emerging type of biospecimen,organoids have great potential for basic science research such as disease modeling,drug resistance mechanism,regenerative medicine,and gene editing,as well as clinical diagnosis and treatment such as typing,drug screening,treatment monitoring,and individualized medicine.Here,we will briefly discuss the current research status,development trend and future prospects of organoid as a"living sample bank",and hope to contribute to the rapid popularization and expansion of this new technology to serve the general health strategy.
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