Effect of rhubarb solution enema on gastrointestinal function recovery after laparoscopic radical resection of colorectal cancer
A prospective,randomized controlled study was conducted to evaluate the safety and efficacy of rhubarb solution enema compared to traditional mechanical intestinal preparation before laparoscopic radical resection of colorectal cancer and provide evidence-based medical evidence for traditional Chinese medicine to accelerate recovery of gastrointestinal functions after abdominal surgery.A total of 237 patients who underwent laparoscopic radical resection of colorectal cancer from December 2018 to April 2021 at the Department of General Surgery and Tumor Surgery of Beijing Traditional Chinese Medicine Hospital,affiliated with Capital Medical University,were included.The patients were divided into two groups:traditional mechanical intestinal preparation and rhubarb solution enema groups.The first exhaust time,first defecation time,bowel sound recovery time,hospitalization time and postoperative stay,quality-of-life score on the fifth postoperative day,degree of abdominal pain and bloating on the first and fifth postoperative days,evaluation of intestinal function,and surgical-related complications in both groups were observed.Patients in the preoperative application of rhubarb solution enema intestinal preparation group had significantly shorter postoperative bowel sound recovery and first postoperative defecation times than those in the traditional mechanical intestinal preparation group,and the difference was statistically significant(P＜0.05).The first postoperative exhaust time for the rhubarb solution enema group was shorter than that for the traditional mechanical intestinal preparation group,but the difference was not statistically significant(P＞0.05).The time for gastric tube removal was earlier in the preoperative rhubarb solution enema intestinal preparation group than in the traditional mechanical intestinal preparation group,and the quality-of-life score on the fifth postoperative day was significantly higher(P＜0.05).The hospitalization days of the rhubarb solution enema intestinal preparation group were lesser than those of the traditional mechanical intestinal preparation group,but the difference was not statistically significant(P＞0.05).Compared with traditional mechanical intestinal preparation,preoperative rhubarb enema intestinal preparation effectively alleviated abdominal distension in patients on the first and fifth postoperative days and reduced gastrointestinal reactions on the fifth postoperative day(P＜0.05).However,there was no significant relief effect on the patients'gastrointestinal response on the first postoperative day or on the degree of abdominal pain on the first and fifth postoperative days(P＞0.05).The other two groups of patients had comparable white blood cell counts on the first and fifth postoperative days,which were not statistically significant(P＞0.05).However,C-reactive protein expression was significantly lower in the rhubarb solution enema intestinal preparation group on the first postoperative day,and the difference was statistically significant(P＜0.01).The expression of C-reactive protein in both groups of patients on the fifth postoperative day was similar but not statistically significant(P＞0.05).There was no significant difference between the two groups in surgical-related complications,such as postoperative incision infection and intestinal obstruction(P＞0.05).The use of rhubarb solution enema for intestinal preparation before laparoscopic radical surgery for colorectal cancer cleans the intestines,accelerates recovery of postoperative bowel sounds,shortens the time for first defecation and indwelling gastric tubes,and,to an extent,alleviates postoperative abdominal distension and gastrointestinal reactions without increasing surgical-related complications.This improves patients'quality of life after surgery and accelerates their recovery.
laparoscopic radical resection of colorectal tumorpreoperative bowel preparationrhubarbtraditional Chinese materia medica enemagastrointestinal function recoverytraditional Chinese medicine enhanced rehabilitation surgery
万方数据
维普
