首页|Recent progress in sulfonyl fluoride synthesis via the radical sulfur dioxide insertion and fluorination strategy

Recent progress in sulfonyl fluoride synthesis via the radical sulfur dioxide insertion and fluorination strategy

Recent progress in sulfonyl fluoride synthesis via the radical sulfur dioxide insertion and fluorination strategy

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Sulfonyl fluoride compounds,as the key components for sulfur(Ⅵ)fluoride exchange(SuFEx)reaction,are characterized by their high chemical stability yet can be selectively activated under specific conditions to enable efficient chemical bonding and connections.This unique capability has garnered significant interest across various domains.Many strategies have been de-veloped for the synthesis of sulfonyl fluoride compounds.This review focuses on the latest advancements in synthesizing these compounds using the radical sulfur dioxide insertion and fluorination(RSIF)strategy,underscoring the versatility and efficacy of the RSIF strategy in constructing sulfonyl fluoride compounds.

organofluorine chemistrysulfonyl fluorideRSIF strategyclick chemistrysynthetic methods

Haozhen Zhang、Wangchuan Xiao、Fanhong Wu、Xiaoyu Ma、Chao Liu

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School of Chemical and Environmental Engineering,Shanghai Institute of Technology,Shanghai 201418,China

Shanghai-Sanming Engineering Research Center of Green Fluoropharmaceutical Technology,Sanming 365004,China

Key Laboratory of Fluorine and Nitrogen Chemistry and Advanced Materials,Shanghai Institute of Organic Chemistry,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Shanghai 200032,China

organofluorine chemistry sulfonyl fluoride RSIF strategy click chemistry synthetic methods

2025

中国科学:化学(英文版)
中国科学院

中国科学:化学(英文版)

影响因子:0.629
ISSN:1674-7291
年,卷(期):2025.68(5)