首页|Local field potentials,spiking activity,and receptive fields in human visual cortex

Local field potentials,spiking activity,and receptive fields in human visual cortex

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The concept of receptive field(RF)is central to sensory neuroscience.Neuronal RF properties have been substantially studied in animals,while those in humans remain nearly unexplored.Here,we measured neuronal RFs with intracranial local field potentials(LFPs)and spiking activity in human visual cortex(V1/V2/V3).We recorded LFPs via macro-contacts and discovered that RF sizes estimated from low-frequency activity(LFA,0.5-30 Hz)were larger than those estimated from low-gamma activity(LGA,30-60 Hz)and high-gamma activity(HGA,60-150 Hz).We then took a rare opportunity to record LFPs and spiking activity via microwires in V1 simultaneously.We found that RF sizes and temporal profiles measured from LGA and HGA closely matched those from spiking activity.In sum,this study reveals that spiking activity of neurons in human visual cortex could be well approximated by LGA and HGA in RF estimation and temporal profile measurement,implying the pivotal functions of LGA and HGA in early visual information processing.

human visual cortexreceptive fieldintracranial EEGlocal field potentialspiking activity

Lu Luo、Xiongfei Wang、Junshi Lu、Guanpeng Chen、Guoming Luan、Wu Li、Qian Wang、Fang Fang

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School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health,Peking University,Beijing 100871,China

School of Psychology,Beijing Sport University,Beijing 100084,China

Department of Neurosurgery,Sanbo Brain Hospital,Capital Medical University,Beijing 100093,China

Beijing Key Laboratory of Epilepsy,Epilepsy Center,Sanbo Brain Hospital,Capital Medical University,Beijing 100093,China

IDG/McGovern Institute for Brain Research,Peking University,Beijing 100871,China

Peking-Tsinghua Center for Life Sciences,Peking University,Beijing 100871,China

Beijing Institute for Brain Disorders,Beijing 100069,China

State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research,Beijing Normal University,Beijing 100875,China

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National Science and Technology Innovation Major Program(2030)National Science and Technology Innovation Major Program(2030)国家自然科学基金国家自然科学基金Beijing Academy of Artificial Intelligence(BAAI)

2022ZD02048022022ZD02048043193005332171039

2024

10.1007/s11427-023-2436-x

中国科学:生命科学(英文版)
中国科学院

中国科学:生命科学(英文版)

CSTPCD
影响因子：0.806
ISSN：1674-7305
年,卷(期)：2024.67(3)
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