具有增强一致性和透气性的无基底超薄表皮生物电极用于长期生理监测

Substrate-free ultra-thin epidermal bioelectrodes with enhanced conformality and breathability for long-term physiological monitoring

李冠军 ¹公彦婷 ¹方诗镪 ¹游通 ¹邵瑞瑞 ¹姚兰前 ¹刘晨 ¹武春锦 ¹牛坚 ¹赖文勇¹

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作者信息

1. State Key Laboratory of Organic Electronics and Information Displays(SKLOEID),Institute of Advanced Materials(IAM),School of Chemistry and Life Sciences,Nanjing University of Posts & Telecommunications,Nanjing 210023,China
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摘要

开发耐用且可靠的生物电极,用以采集高质量的生物电信号,已成为人体生理状态监测和人机交互领域的关键技术.然而,现有的生物电极多基于传统弹性基底,这导致了机械性能不匹配和低渗透性等问题,并且缺乏与生物皮肤类似的多方面属性和必要的协同特性.本研究中,我们报道了一种新型的基于自支撑导电全聚合物薄膜的超薄表皮生物电极(ASU-EBE).该电极将超一致性、优异的拉伸性和透气性集成于一体,展现了约475 S cm-1的高导电性,约48％的出色拉伸性,与生物组织界面的超一致性以及优异的透气性.该电极的电子和机械性能得到提升,这归功于在PEDOT:PSS中引入水溶性聚氧化乙烯,以调节分子间π-π堆积距离,并促进纳米纤维结构的形成.因此,ASU-EBE在与皮肤接触时的阻抗远低于标准凝胶电极,使其成为复杂日常环境下长期医疗监测的理想选择.

Abstract

The development of durable and reliable bioe-lectrodes for high-quality bioelectrical signals acquisition has become a crucial technology in the field of human physiolo-gical condition monitoring and human-machine interfaces.However,most existing bioelectrodes are limited to conven-tional elastomeric substrates that suffer from mechanical mismatch and low permeability,and lack multifaceted attri-butes and essential synergistic properties akin to those found in biological skins.In this work,we report advanced substrate-free ultra-thin epidermal bioelectrodes(ASU-EBEs)based on free-standing conductive all-polymer(FCAP)films,which integrate the advantages of ultra-conformality,excellent stretchability and breathability into a single device.The re-sulting ASU-EBEs exhibit excellent conductivity of-475 S cm-1,outstanding stretchability of-48％,ultra-con-formality to the interface of biological tissues and superior breathability.The enhanced electronic and mechanical per-formance is attributed to the introduction of water-soluble polyethylene oxide into poly(3,4-ethylenedioxythiophene):poly(4-styrenesulfonate)(PEDOT:PSS)to control the mole-cular π-π stacking distance and promote the formation of nanofiber structures.Hence,ASU-EBEs show much lower skin-contact impedance than the standard gel electrodes,en-abling the use for long-term healthcare monitoring in complex daily conditions.

关键词

flexible bioelectronics/epidermal bioelectrodes/free-standing conductive films/conformality/breathability

Key words

flexible bioelectronics/epidermal bioelectrodes/free-standing conductive films/conformality/breathability

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基金项目

National Key Research and Development Program of China(2023YFB3608904)

National Natural Science Foundation of China(21835003)

National Natural Science Foundation of China(61704077)

Natural Science Foundation of Jiangsu Province(BE2019120)

Natural Science Foundation of Jiangsu Province(BK20191374)

Foundation of Key Laboratory of Flexible Electronics of Zhejiang Province(2023FE002)

Natural Science Foundation of Jiangsu Higher Education Institutions of China(18KJB150025)

Program for Jiangsu Specially-Appointed Professor(RK030STP15001)

Postgraduate Research &Practice Innovation Program of Jiangsu Province(KYCX21_0778)

Postgraduate Research &Practice Innovation Program of Jiangsu Province(SJCX21_0298)

NUPT Scientific Foundation(NY219021)

NUPT Scientific Foundation(NY219109)

Leading Talent of Technological Innovation of National Ten-Thousands Talents Program of China()

Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)()

出版年

2024

中国科学:材料科学(英文)

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ISSN：

段落导航