生物材料介观结构组装及工程化的最新进展、挑战和前景

State-of-the-art,challenges,and prospects in mesoscopic structural assembly and engineering technologies within biomaterials

焦芸可 ¹雷淼 ¹唱荣航 ¹屈雪²

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作者信息

1. Key Laboratory for Ultrafine Materials of Ministry of Education,School of Material Science and Engineering,Frontiers Science Center for Materiobiology and Dynamic Chemistry,East China University of Science and Technology,Shanghai 200237,China
2. Key Laboratory for Ultrafine Materials of Ministry of Education,School of Material Science and Engineering,Frontiers Science Center for Materiobiology and Dynamic Chemistry,East China University of Science and Technology,Shanghai 200237,China;Wenzhou Institute of Shanghai University,Wenzhou 325000,China;Shanghai Frontier Science Center of Optogenetic Techniques for Cell Metabolism,Shanghai 200237,China
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摘要

尽管天然生物组织的组分性能有限,但其跨越多尺度的复杂有序结构赋予了其出色的功能,这一点在介观尺度尤为显著.介观结构在调控材料的物理性质和生物活性方面发挥着至关重要的作用.本文深入探讨了对组织再生修复材料进行介观结构控制的挑战,并提出了一种新型的场调控动态自组装技术.该技术以电化学沉积技术为基础,通过调控电化学参数或与其他物理场进行耦合,能够更精准地控制生物大分子组装体的介观结构,从而实现材料的高性能化.此外,本文还讨论了该技术在工程化应用上的优势.最后强调了跨学科和跨部门合作的重要性,这对于推动生物材料制造技术的产业化和商业化至关重要.总之,该技术在组织再生领域展现出了广阔的发展前景.

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基金项目

National Key Research and Development Program(2021YFB3800800)

National Natural Science Foundation of China(31922041)

National Natural Science Foundation of China(32171341)

National Natural Science Foundation of China(32301113)

111 Project(B14018)

Science and Technology Innovation Project and Excellent Academic Leader Project of Shanghai Science and Technology Committee(21S31901500)

Science and Technology Innovation Project and Excellent Academic Leader Project of Shanghai Science and Technology Committee(21XD1421100)

National Postdoctoral Program for Innovative Talents(BX20230122)

Shanghai Sailing Program(23YF1409700)

Shanghai Postdoctoral Excellence Program(2022157)

China Postdoctoral Science Foundation(2022M721136)

出版年

2024

中国科学:材料科学(英文)

CSTPCD

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