艾司西酞普兰与帕罗西汀治疗抑郁症的对照研究
Comparative study between escitalopram and paroxetine in the treatment of depression
郝剑辉 1郭娅慧 1郝晓瑞 2张渊2
作者信息
- 1. 030800,山西省荣军精神康宁医院
- 2. 晋中市第二人民医院
- 折叠
摘要
目的 观察艾司西酞普兰治疗抑郁症的疗效及安全性.方法 将68例抑郁症患者随机分为艾司西酞普兰组和帕罗西汀组,疗程6周,以汉密尔顿抑郁量表(HAMD)和汉密尔顿焦虑量表(HA-MA)评定疗效,以症状用量表(TESS)评定不良反应.结果 艾司西酞普兰组和帕罗西汀组有效率分别为94.1%和91.1%,两组疗效差异无显著性意义,但治疗1周后艾司西酞普兰组有效率高于帕罗西汀组.结论 艾司西酞普兰是一种安全有效的抗抑郁药.
Abstract
Objective To observe the clinical efficacy and safety of escitalporam in the treatment of depression. Methods 68 patients with depression randomly devided into escitalopram group and paroxetine group for 6 weeks. clinical efficacy was evaluated using Hamilton depression scale(HAMD) and Hamilton anxiety scale (HAMA) and treatment emergent symptoms scales(TESS)were used to evaluate the advense effects. Results The effective rate of escitalopram was94. 1% and paroxetine group was91.1%. Escitalopram group showed a highter response rate compared with paroxetine group after one week treatment. Conclusion Escitalopram is an effective and safe drug in the treatment of depression.
关键词
艾司西酞普兰/帕罗西汀/抑郁症Key words
Escitalopram/Paroxetine/Depression引用本文复制引用
出版年
2010
NETL
NSTL
维普
万方数据