Efficacy and safety of interventional therapy combined with drug in-jection under bronchoscope in the treatment of central non-small cell lung cancer
AIM:To evaluate the efficacy and safe-ty of interventional therapy combined with tumor drug injection under bronchoscope for central non-small cell lung cancer(NSCLC).METHODS:Sixty-four patients who met the test admission criteria were randomly assigned to the experimental group and the control group according to the ratio of 1:1,and were given bronchoscopic interventional thera-py combined with local drug injection of recombi-nant human endostatin combined with platinum-containing dual-drug chemotherapy and platinum-containing dual-drug alone,respectively.The cura-tive efficiency and safety of the two groups were compared.RESULTS:Compared with the control group,the KPS score,dyspnea grading were signifi-cantly improved(P＜0.05).The effective rate of the test group was 78.12％,which was higher than 37.5％in the control group,the difference between the two groups was significant(P＜0.05).Moreover,there was also a significant difference in the 1-year survival rate between the experimental group and the control group(P＜0.05).CONCLUSION:The treatment of central NSCLC by interventional thera-py combined with tumor drug injection through fi-beroptic bronchoscope has obvious clinical efficacy,which can effectively alleviate the clinical symp-toms and improve the quality of life of patients.There is no significant difference in adverse reac-tions between the two groups,and is worthy of popularization and application.
国家科技期刊平台
NSTL
万方数据
维普
