The application of positron emission tomography in the research and development of central nervous system drugs
Positron emission tomography(PET)now plays an important role in the research and de-velopment(R&D)of central nervous system(CNS)drugs.PET could characterize the biodistribution,pharmacokinetics,and receptor binding of CNS drugs quantitatively.The present review summa-rized the quantitative methods of PET used in the pharmacokinetics and receptor occupancy analysis of CNS drugs.Moreover,the present review listed various applications of PET supporting R&D of CNS drugs,which could provide a new direction for the R&D of CNS drugs.
positron emission tomographycen-tral nervous systemthe research and development of new drugspharmacokineticsreceptor occupan-cy
国家科技期刊平台
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