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诱导痰检测在慢性气道病中的应用及发展前景

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诱导痰检测是一种可反映气道炎症性质及程度的非侵袭性检测手段,在慢性气道疾病中的诊断、治疗和预后中均发挥了重要作用。本文概述了诱导痰技术的发展历史,介绍了诱导痰技术的原理与操作方法,评估了其安全性,归纳了三大主要检测内容,详实地阐述了该技术在各慢性气道疾病中的作用,如反映气道炎症类型、预测药物疗效及与转录组学结合进行疾病机制研究等,并简要梳理了其创新性,做出未来愿景。
Induced sputum testing in chronic airway disease and the prospects for its development
Induced sputum testing is a non-inva-sive test that reflects the nature and extent of air-way inflammation and plays an important role in the diagnosis,treatment and prognosis of chronic airway diseases.This article outlines the develop-ment history of induced sputum technology,intro-duces the principle and operation of induced spu-tum technology,evaluates its safety,summarizes the three main test components,elaborates the role of this technology in various chronic airway diseases,such as reflecting the type of airway in-flammation,predicting the efficacy of medication,and combining it with transcriptomics to study dis-ease mechanisms,and briefly summarizes its inno-vations and makes a vision for the future.

induced sputum techniquechronic airway diseaseapplication progressprospects for development

高佳萌、沈瑶、薛丽萍、陈智鸿

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复旦大学附属中山医院呼吸与危重医学科,上海 200032

上海市浦东医院,复旦大学附属浦东医院,呼吸与危重症医学科,上海 201399

诱导痰技术 慢性气道病 应用进展 发展前景

国家自然科学基金国家自然科学基金

8197002382270026

2024

中国临床药理学与治疗学
中国药理学会

中国临床药理学与治疗学

CSTPCD北大核心
影响因子:0.97
ISSN:1009-2501
年,卷(期):2024.29(4)
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