特纳综合征高血压的研究进展
Research progress on association between Turner syndrome and high blood pressure
刘继纯 1胡思思 1葛涛 1谢向荣1
作者信息
- 1. 皖南医学院第一附属医院(弋矶山医院)心内科,芜湖 241000,安徽
- 折叠
摘要
特纳综合征是临床表型为女性的性染色体病.大部分患者常因生长发育迟缓在儿童或青少年时期被确诊,少部分患者因特纳综合征相关疾病就诊被诊断.特纳综合征的女性在儿童期和青少年时期就可出现高血压,高血压患病率随年龄增长而增加,其发病机制尚不清楚,可能是多因素的,与原发性高血压相似.本综述探讨特纳综合征患者高血压的可能机制、血压管理和治疗建议.
Abstract
Turner syndrome is a sex chromosome disease with a female clinical phenotype.Most pa-tients are diagnosed in childhood or adolescence because of growth delays,and a small number of patients are diagnosed due to TS-related diseases.Women with Turner syndrome can develop hyper-tension in childhood and adolescence,and the prevalence of hypertension increases with age.The pathogenesis is unclear and may be multifactorial,similar to essential hypertension.In this review arti-cle,we explore possible mechanisms,blood pres-sure management,and treatment recommenda-tions for hypertension in patients with Turner syn-drome.
关键词
高血压/特纳综合征/性染色体病Key words
high blood pressure/Turner syn-drome/sex chromosomal disease引用本文复制引用
基金项目
安徽省高等学校科研计划自然科学重点项目(2022AH051238)
安徽省临床重点专科建设项目(KZSJZ008)
皖南医学院中青年科研基金(WK2023ZQNZ23)
出版年
2024
国家科技期刊平台
NSTL
万方数据