中国临床药理学与治疗学2024,Vol.29Issue(8) :947-954.DOI:10.12092/j.issn.1009-2501.2024.08.012

灵芝活性成分抗肿瘤机制研究进展

Progress on anti-tumor mechanisms of Ganoderma lucidum active in-gredients

吕俞娇 周姝婷 王丽娜 沈明妹 刘永超
中国临床药理学与治疗学2024,Vol.29Issue(8) :947-954.DOI:10.12092/j.issn.1009-2501.2024.08.012

灵芝活性成分抗肿瘤机制研究进展

Progress on anti-tumor mechanisms of Ganoderma lucidum active in-gredients

吕俞娇 1周姝婷 2王丽娜 1沈明妹 1刘永超1
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作者信息

  • 1. 北华大学医学技术学院,吉林 132013,吉林
  • 2. 北华大学口腔医学院,吉林 132013,吉林
  • 折叠

摘要

恶性肿瘤是我国慢性病死亡的主要原因之一,其发病率和死亡率呈现逐年增加趋势.恶性肿瘤的晚期非手术治疗是改善患者预后,提高其生存质量的重要手段.传统中药灵芝具有抗肿瘤作用,在多种恶性肿瘤治疗中发挥作用.本文就近五年来国内外应用灵芝活性成分针对肿瘤的作用研究进行系统综述,探讨灵芝活性成分抗肿瘤的作用机制,为灵芝活性成分应用于临床奠定理论基础.

Abstract

Malignant tumors are one of the main causes of death from chronic diseases in China,and their incidence and mortality rates show an in-creasing trend year by year.Advanced non-surgical treatment of malignant tumors is an important means of improving patients'prognosis and en-hancing their quality of life.The traditional Chinese medicine Ganoderma lucidum has anti-tumor ef-fects and plays a role in the treatment of many ma-lignant tumors.In this paper,a systematic review of the effects of Ganoderma lucidum active ingredi-ents on tumors has been conducted at home and abroad in the past five years to explore the anti-tu-mor mechanism of Ganoderma lucidum active in-gredients and to lay a theoretical foundation for the application of Ganoderma lucidum active ingre-dients in clinical practice.

关键词

灵芝/灵芝多糖/灵芝三萜/灵芝酸/抗肿瘤

Key words

ganoderma lucidum/ganoderma lu-cidum polysaccharide/ganoderma lucidum triter-pene/ganoderic acid/antitumor

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基金项目

吉林省科技发展计划项目(20220402072GH)

出版年

2024
中国临床药理学与治疗学
中国药理学会

中国临床药理学与治疗学

CSTPCD北大核心
影响因子:0.97
ISSN:1009-2501
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