血压变异性与认知障碍关系研究进展

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中文摘要：认知障碍是导致老年人人格及行为能力减退的一种老年疾病,严重影响患者日常生活质量.认知障碍患病率随社会老龄化进程加快而逐年升高.认知障碍发病受众多危险因素影响.现阶段中晚期认知障碍患者的疗效欠佳.因此,早期识别、干预以延缓病情进展成为目前相关研究的焦点.血压变异性能够导致心脏、脑组织及肾脏等靶器官的损害,与认知障碍密切相关.为拓展认知障碍早期干预的新视角,本文综述了血压变异性对不同认知障碍疾病的影响及其可能的致病机制.

外文标题：Research progress on the relationship between blood pressure variability and cognitive impairment

外文摘要：Cognitive impairment is a kind of senile disease that leads to the decline of personality and behavior ability of the elderly,which seriously affects the quality of daily life of patients.The prevalence rate of the disease increases year by year with the acceleration of the aging process of the society,and its incidence is affected by many risk factors.At this stage,the curative effect for middle and advanced patients is poor.So early identification and intervention to delay the progression of cognitive impairment have become the focus of relevant research.Blood pressure variability can lead to damage of target organs such as heart,brain tissue and kidney,which is closely related to cognitive impairment.In order to expand a new perspective of early intervention in cognitive impairment,this paper reviews the effects of blood pressure variability on different cognitive impairment and its possible pathogenic mechanism.

外文关键词：

cognitive impairmentAlzheimer s diseasecerebral small vessel diseaseblood pressure variability

作者：

侯阿龙、程文彬、孙文静、陈晓晗、李根茹、庄建华、尹又

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作者单位：

海军军医大学第二附属医院神经内科,上海 200003

关键词：

认知障碍阿尔茨海默病脑小血管病血压变异性

基金：

上海市"科技创新行动计划"医学创新研究专项上海市自然科学基金医院创新型临床研究项目长征医院为军特色医疗服务项目长征医院临床研究性项目

项目编号：

23Y1190660022ZR1477502020YLCYJ-Y022020CZWJFW122023YJBF-PY13

出版年：

2024

DOI：

10.12025/j.issn.1008-6358.2024.20232042

中国临床医学

复旦大学附属中山医院

中国临床医学

CSTPCD

影响因子：1.002

ISSN：1008-6358

年,卷(期)：2024.31(4)