FS-T2WI联合DWI在乳腺良恶性囊实性病变鉴别诊断中的价值
Value of FS-T2WI combined with DWI in the differential diagnosis of benign and malignant cystic solid lesions of the breast
郑海龙 1严高武1
作者信息
- 1. 遂宁市中心医院放射影像科,四川 遂宁 629000
- 折叠
摘要
目的:探究T2WI 抑脂序列(Fat saturation T2-weighted imaging,FS-T2WI)联合扩散加权成像(Diffusion weighted imaging,DWI)在乳腺良恶性囊实性病变鉴别诊断中的价值.方法:回顾性选取 2021 年 1 月—2022 年 12 月于我院治疗的乳腺囊实性病变患者 95 例,病灶数量 113 个.于治疗前对患者行FS-T2WI和DWI序列扫描,对影像学图像进行分析,获取ADC值和FS-T2WI不均匀,以手术病理检查结果为金标准,采用受试者工作曲线(ROC)分析FS-T2WI和DWI序列扫描对乳腺良恶性囊实性病变的鉴别效能.结果:对 95 例患者行病理组织活检,有 38 例患者存在恶性结节,57 例患者无恶性结节,根据此结果将患者分为良性组和恶性组,比较两组患者资料发现,恶性组患者的结节数量明显多于良性组,最大肿瘤直径大于良性组(P<0.05).病理检查结果显示共有 113 个结节,其中恶性结节 48 个,良性结节 65 个.根据结节性质不同将结节分为良性结节和恶性结节,比较不同结节的FS-T2WI和DWI序列扫描结果发现,良恶性结节囊壁特点、厚度和肿瘤内部强化特征之间差异有统计学意义,且恶性结节平均直径大于良性结节,ADC值和SIR值小于良性结节(P<0.05).ADC值和SIR值对乳腺囊实性良恶性病变的诊断AUC分别为 0.801、0.818,两者联合检测的AUC为 0.908,其联合诊断灵敏度和特异度分别为 81.3%、86.3%,高于单独诊断的诊断效能.结论:FS-T2WI和DWI序列扫描对于乳腺囊实性良恶性病变均有较高的鉴别诊断价值,且两者联合诊断的灵敏度和特异度均高于单独诊断.
Abstract
Objective:To explore the value of fat saturation T2-weighted imaging(FS-T2WI)combined with diffusion weight-ed imaging(DWI)in the differential diagnosis of benign and malignant cystic and solid lesions of the breast.Methods:A ret-rospective study was conducted on 95 cases with cystic and solid lesions of breast treated in our hospital from January 2021 to December 2022,with a total of 113 lesions.Before treatment,the patients were scanned with FS-T2WI and DWI sequence,and the images were analyzed to obtain ADC values and FS-T2WI nonuniformity.The results of surgical pathology were used as the gold standard.The receiver operator curve(ROC)was used to analyze the differential efficacy of FS-T2WI and DWI se-quence scanning in benign and malignant cystic and solid breast disease.Results:Pathological tissue biopsies were performed on 95 cases,38 cases had malignant nodules and 57 cases had no malignant nodules.According to the results,the patients were divided into benign group and malignant group.Comparing the data of patients in the two groups,it was found that the number of nodules in the malignant group was significantly greater than that in the benign group,and the diameter of the largest tumor was larger than that in the benign group(P<0.05).Pathological examination showed that there were 113 nodules,including 48 malignant nodules and 65 benign nodules.According to the different nature of the nodules,they were divided into benign and malignant nodules.Comparing the FS-T2WI and DWI sequence scanning results of different nodules,it was found that there were statistically significant differences in the characteristics,thickness,and internal enhancement characteris-tics of the cyst wall between benign and malignant nodules.The average diameter of malignant nodules was larger than that of benign nodules,and the ADC and SIR values were smaller than those of benign nodules(P<0.05).The AUC of ADC value and SIR value for the diagnosis of benign and malignant cystic and solid breast lesions were 0.801 and 0.818,respectively,and the AUC of the combined detection of the two was 0.908.The sensitivity and specificity of the combined diagnosis were 81.3%and 86.3%,respectively,which were higher than the diagnostic efficacy of the single diagnosis.Conclusion:FS-T2WI and DWI sequence scanning have high value in differential diagnosis of breast cystic solid benign and malignant lesions,and the sensitivity and specificity of the combined diagnosis of both are higher than those of single diagnosis.
关键词
乳腺肿瘤/乳腺疾病/磁共振成像Key words
Breast Neoplasms/Breast Diseases/Magnetic Resonance Imaging引用本文复制引用
基金项目
四川省卫生健康委科研项目(19PJ284)
出版年
2024
国家科技期刊平台
NSTL
万方数据