Objective:To explore the evaluation value of three-dimensional arterial spin labeling imaging(3D-ASL)and susceptibility weighted imaging(SWI)for cerebral blood perfusion in patients with acute cerebral infarction(ACI).Methods:A total of 78 patients with ACI admitted to the hospital were enrolled between December 2020 and December 2022.All under-went routine MRI,SWI and 3D-ASL.According to MRI results,they were divided into symptomatic group(n=57)and asymp-tomatic group(n=21).The prominent hypointense vessels signs(PHVS)in SWI images were graded by semi-quantitative Alberta stroke program early CT score(ASPECTS).The rCBF values were detected by 3D-ASL.ASPECTS and rCBF were compared between the symptomatic group and the asymptomatic group.The disease severity in ACI patients was evaluated by National Institutes of Health Stroke Scale(NIHSS).ASPECTS and rCBF in patients with different disease severity were compared.The relationship between ASPECTS,rCBF and NIHSS score was analyzed by Pearson correlation analysis.Results:ASPECTS in the asymptomatic group was lower than that in the symptomatic group,and rCBF was greater than that in the symptomatic group(P＜0.05).According to NIHSS scores,ACI patients were divided into mild group(n=19),moderate group(n=32)and severe group(n=27).ASPECTS in mild group was lower than that in moderate and severe groups,while rCBF was greater than that in moderate and severe groups(P＜0.05).Compared with moderate group,ASPECTS was higher,and rCBF was lower in severe group(P＜0.05).Pearson correlation analysis showed that NIHSS score was positively correlated with ASPECTS(r=0.386),while negatively correlated with rCBF(r=-0.414,P＜0.05).Conclusion:Both 3D-ASL and SWI were valuable for disease severity e-valuation.However,compared with SWI,3D-ASL is better for clinical evaluation of cerebral blood perfusion in ACI patients.
维普
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