Objective:To evaluate the changes of right ventricular systolic function in patients with obstructive sleep ap-nea syndrome(OSAS)using the two-dimensional speckle tracking imaging(2D-STI)technique.Methods:Forty-nine patients with OSAS diagnosed by polysomnography were divided as the OSA group.Based on the sleep AHI,there were 12 cases classified as mild,9 as moderate,and 28 as severe.Forty healthy volunteers with matching age and gender and without a history of snoring were selected as the control group.They underwent conventional echocardiography and 2D-STI to complete the analysis of right ventricular,and variables were compared between the two groups.Results:Compared with the control group,the OSA group showed significantly higher right atrial volume index(RAVI)(P=0.04),and the peak of late diastolic flow velocity of tricuspid orifice(A-tv)was significantly increased(P=0.025).The value of E/A was decreased(P=0.047),and early peak diastolic velocity(Ea)of tricuspid annulus by TDI was significantly decreased(P=0.014).The global longitudinal strain of right ventricle(RV-GLS)(P=0.036)and longitudinal strain of right ventricular free wall(RV-FWLS)(P=0.039)in the OSA group were significantly reduced.Compared to the mild and moderate OSA,RV-GLS of the severe OSA showed a notable reduction(P=0.002),as well as RV-FWLS(P=0.030).Meanwhile RVFW basal longitudinal strain(P=0.033)and apex longitudinal strain(P=0.028)of severe OSA were significantly reduced,and RVFW middle longitudinal strain was not significantly different between two groups(P＞0.05).Conclusion:The diastolic and systolic functions of right ventricular are changed in patients with OSAS.2D-STI can detect the changes in right ventricular systolic function at an early stage,related to the severity of the syndrome.RVLS can be used as an important clinical parameter and provides valuable information for clinical treatment and prognosis.
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