Objective:To evaluate the value of prenatal fetal position,angle of progression(AOP),and head-perineum dis-tance(HPD)in predicting the mode of childbirth.Methods:A total of 330 full-term nulliparous women without contraindica-tions to trial of labor from July 2021 to August 2022 in our hospital were invovled and divided into vaginal delivery group(n=282)and cesarean section group(n=48),according to the outcome of delivery.Data on pregnant women and fetal biparietal di-ameter,femur length,head circumference,and abdominal circumference one week prior to delivery were gathered.The last vaginal fingerprinting for Bishop's score,the ultrasound measurements of fetal orientation,AOP,and HPD results were record-ed prior to labor after admission to the hospital.The relationship between these parameters and mode of delivery was ana-lyzed,and the effectiveness of the relevant indicators in predicting labor was assessed.Results:Multi-factor regression analysis showed that maternal height,Bishop score,newborn weight,and AOP were correlated with vaginal delivery(P<0.05);the area under the curve of AOP predicting vaginal delivery was 0.852,with sensitivity of 85.1%and specificity of 79.2%.The rate of vaginal delivery was statistically significant(52.5%vs 96.0%,P<0.001)between the two groups with AOP<91.5° and ≥91.5°.Conclusion:Prenatal ultrasound measurement of AOP is related to mode of delivery,and a larger AOP increases the chance of vaginal delivery for primiparous women.Combining AOP with maternal andneonatal indicators can improve the accuracy of prediction.