摘要
目的:探讨超声引导下乳腺旋切技术治疗乳腺良性肿瘤的优势及对血清CEA和CA125 水平的影响.方法:前瞻性选择 2021 年 1 月—2022 年 12 月在本院诊治的乳腺良性肿瘤患者 110 例作为研究对象,以数字表法将其分成观察组和对照组,各 55 例.对照组应用传统手术治疗,观察组应用超声引导下乳腺旋切技术治疗,对比两组手术相关指标,乳房外观美观度,血清CEA与CA125 水平,术后并发症发生情况,肿块残留与复发情况.结果:观察组患者手术时间、切口愈合时间及住院时间均较对照组短(P＜0.05),术后 24h疼痛程度评分与术中出血量均较对照组低(P＜0.05);术后 1 年观察组患者的乳房外观美观度显著优于对照组(P＜0.05);治疗后两组血清CEA与CA125 水平较治疗前低(P＜0.05),且观察组血清CEA、CA125 水平较对照组低(P＜0.05);应用超声引导下乳腺旋切技术的观察组并发症总发生率显著低于应用传统手术治疗的对照组(P＜0.05);观察组患者的乳房畸形率较对照组低(P＜0.05),且未发生肿块残留及复发情况.结论:应用超声引导下乳腺旋切技术对乳腺良性肿瘤患者实施治疗,效果较为显著,不仅能够改善手术相关指标,减轻疼痛,还能提高患者乳房外观美观度,降低血清CEA、CA125 水平,同时肿块无残留及复发情况,不良并发症少,安全性较高,值得临床深入推广.
Abstract
Objective:To explore the advantages of ultrasound-guided breast circumcision in the treatment of benign breast tumors and its effect on serum CEA and CA125 levels.Methods:In this study,we selected 110 patients who had been diagnosed and treated for benign breast tumors at our hospital between January 2021 and December 2022.These indi-viduals were split into two groups,the observation group and the control group,each consisting of 55 patients,using a ran-dom digital table method.Patients in the control group underwent traditional surgical procedures,whereas those in the obser-vation group received breast lumpectomy procedures guided by ultrasound.Compared with the two groups,the indexes related to surgery,the appearance of the breast,the level of serum CEA and CA125,the occurrence of postoperative complications,the residual and recurrence of the tumor.Results:For patients in the observation group,the duration of the operation,the time taken for wound healing,and the duration of hospitalization was observed to be notably reduced when compared with the control group,exhibiting a statistically significant disparity(P＜0.05);The postoperative pain score after 24 h and intraoperative bleeding volume were lower than those in the control group(P＜0.05).One year after operation,the patients in the observation group had significantly better breast appearance than those in the control group(P＜0.05);Following therapy,the levels of serum CEA and CA125 in both groups decreased compared to pre-treatment levels(P＜0.05),and these levels in the observation group were further reduced in comparison to the control group(P＜0.05).The total incidence of complications in the observation group with ultrasonic breast circumcision was significantly lower than that in the control group with traditional surgical treatment(P＜0.05).The rate of breast deformity in the observation group was lower than that in the control group(P＜0.05),and there was no residual mass or recurrence.Conclusion:The application of ultrasound-guided breast circumcision in the treatment of pa-tients with benign breast tumors has a relatively significant effect.It can not only improve the relevant indicators of surgery,reduce pain,but also improve the appearance of the patients'breasts,reduce the serum CEA and CA125 levels.At the same time,there is no residual and recurrence of the tumor,less adverse complications,and higher safety,which is worthy of fur-ther clinical promotion.
基金项目
吴阶平医学基金会临床科研专项(320.6750.2022-19-43)
维普
万方数据