Objective:To investigate the predictive value of MRI quantitative parameters in vascular invasion of rectal cancer.Methods:The clinicopathologic and MRI data of 120 patients with rectal cancer were analyzed retrospectively.Ac-cording to the pathological results,the patients were divided into positive group and negative group of vascular invasion.The differences of clinicopathologic and MRI characteristic parameters between the two groups were analyzed,and the independent influencing factors of vascular invasion of rectal cancer were analyzed by binary Logistic regression.Area under the curve(AUC)of receiver operating characteristic curve(ROC)was used to evaluate its prediction efficiency.Results:①A total of 120 patients were enrolled in this study,including 38 patients(31.67%,38/120)in the positive vascular invasion group and 80 pa-tients(68.33%,82/120)in the negative vascular invasion group.Patients with rectal cancer complicated with nerve invasion and lymph node metastasis were more likely to have vascular invasion,and the difference between the two groups was statistically significant(all P<0.05).②In MRI quantitative parameters,patients with higher Ve value were more likely to have vascular in-vasion,and the difference between the two groups was statistically significant(P<0.05).③Logistic regression analysis showed that positive lymph nodes were an independent risk factor for vascular invasion(P<0.05),with an AUC of 0.911.Conclusion:Lymph node positive status is an independent risk factor for vascular invasion of rectal cancer and has high diagnostic efficacy.