Objective:To investigate the clinical value of high-definition flow(HD-Flow)combined with spatiotemporal im-age correlation(STIC)in the diagnosis of fetal pulmonary atresia with ventricular septal defect(PA-VSD).Methods:The two-di-mensional images and HD-Flow combined with STIC images of 44 PA-VSD fetuses diagnosed by fetal echocardiography were analyzed,so as to evaluate the efficacy of HD-Flow combined with STIC in the diagnosis of different subtypes of PA-VSD,the relationship between the inner diameter of PA-VSD fetal ductus arteriosus and the inner diameters of left and right pul-monary artery was studied.Results:HD-Flow combined with STIC diagnosis was performed in 44 cases,including 42 cases of type A and 2 cases of type C.HD-Flow combined with STIC can clearly display the fetal pulmonary artery and its branches and ductus arteriosus blood flow.Pearson correlation analysis showed that the A-type ductus diameter was positively correlated with the left and right pulmonary artery diameters(r=0.507,0.404,P<0.01).Conclusion:HD-Flow combined with STIC can clearly diagnose PA-VSD and classify it,which has great clinical application value.There is a positive correlation between the diameter of fetal ductus arteriosus and the diameters of left and right pulmonary artery in type A PA-VSD.